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N20C hydrochloride

Name: N20C hydrochloride
Brand: TargetMol
SKU: T23048
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T23048Cas No. 1177583-87-7

Alias 2-((3,3-diphenylpropyl)amino)acetamide hydrochloride

N20C hydrochloride (2-((3,3-diphenylpropyl)amino)acetamide hydrochloride) is a non-competitive NMDA receptor open-channel blocker.

N20C hydrochloride

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Purity: 99.9%

Catalog No. T23048Alias 2-((3,3-diphenylpropyl)amino)acetamide hydrochlorideCas No. 1177583-87-7

N20C hydrochloride (2-((3,3-diphenylpropyl)amino)acetamide hydrochloride) is a non-competitive NMDA receptor open-channel blocker.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$34	-	In Stock
5 mg	$79	-	In Stock
10 mg	$95	-	In Stock
25 mg	$209	-	In Stock
50 mg	$303	-	In Stock
100 mg	$413	-	In Stock
200 mg	$548	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.9%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

N20C hydrochloride AI Summary

N20C hydrochloride exhibits a diverse range of bioactivities, including receptor agonism, enzyme inhibition, and enzyme activation. It acts as an agonist of the Thyroid Stimulating Hormone Receptor, leading to activation of intracellular cAMP concentrations in Parental HEK 293 cells. Additionally, it shows inhibitory activity against 15-human lipoxygenase, 15-human lipoxygenase 2, and the Human Apurinic/apyrimidinic Endonuclease 1. Furthermore, N20C hydrochloride activates Cytochrome P450 3A4. It also demonstrates antiviral activity, showing inhibition of SARS-CoV-2-induced cytotoxicity in Caco-2 cells (5.59% at 10 µM after 48 hours) and in VERO-6 cells (0.18% at 10 µM after 48 hours). Moreover, it acts as a SARS-CoV-2 3CL-Pro protease inhibitor with 11.65% inhibition at a concentration of 20 µM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	N20C hydrochloride (2-((3,3-diphenylpropyl)amino)acetamide hydrochloride) is a non-competitive NMDA receptor open-channel blocker.
Synonyms	2-((3,3-diphenylpropyl)amino)acetamide hydrochloride

Chemical Properties

Molecular Weight	304.81
Formula	C₁₇H₂₁ClN₂O
Cas No.	1177583-87-7
Smiles	Cl.O=C(N)CNCCC(C=1C=CC=CC1)C=2C=CC=CC2
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 25 mg/mL (82.02 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.2807 mL	16.4037 mL	32.8073 mL	164.0366 mL
5 mM	0.6561 mL	3.2807 mL	6.5615 mL	32.8073 mL
10 mM	0.3281 mL	1.6404 mL	3.2807 mL	16.4037 mL
20 mM	0.1640 mL	0.8202 mL	1.6404 mL	8.2018 mL
50 mM	0.0656 mL	0.3281 mL	0.6561 mL	3.2807 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc