n 2

Human Notch 2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of either Notch-1 or Notch 2 is lethal, showing that not all functions overlap.Notch 2 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ RBPSUH and activates genes of the enhancer of split locus.

Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of either Notch-1 or Notch-2 is lethal, showing that not all functions overlap.Notch-2 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ RBPSUH and activates genes of the enhancer of split locus.

Expression system: E. coli
Length: 1-159, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 2-131, Full Length of Mature Protein
Activity: Not Tested

LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4 CD85k ILT3 SR & Domain 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.16 kDa and the accession number is AAH26309.1.

Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.

Expression system: E. coli
Length: 1-278, Full Length
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-278, Full Length
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-278, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-694, Partial
Activity: Not Tested

VEGFR2 KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is P35968-1.

Desmocollin 2 DSC2 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is P55292.

TAG1 Contactin 2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 109 kDa and the accession number is A1ML24.

Expression system: Baculovirus Insect Cells
Length: 1-278, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 60-166, Full Length
Activity: Enzyme activity

Expression system: HEK293 Cells
Length: 31-1013, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-205 (mutation), Partial
Activity: Cell Activity

Expression system: E. coli
Length: 1-300, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-22, Partial
Activity: Not Tested

Expression system: E. coli
Length: 22-81, Full Length of Mature Protein
Activity: Not Tested

Kallikrein 2 KLK2 Protein, Human, Recombinant (Yeast, His) is expressed in Yeast. The accession number is P20151.

Human Fc gamma RIIIA CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 35.29 kDa and the accession number is AAH17865.

Desmocollin 2 DSC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.89 kDa and the accession number is Q02487-1.

VEGFR2 KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.4 kDa and the accession number is P35968-1.