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Anti-PDCD1LG2 Antibody (5N738)
Catalog No. TMAB-10096 Copy Product Info
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Anti-PDCD1LG2 Antibody (5N738) is a Mouse antibody targeting PDCD1LG2. Anti-PDCD1LG2 Antibody (5N738) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-PDCD1LG2 Antibody (5N738)
Copy Product Info🥰Excellent
Catalog No. TMAB-10096
Anti-PDCD1LG2 Antibody (5N738) is a Mouse antibody targeting PDCD1LG2. Anti-PDCD1LG2 Antibody (5N738) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-PDCD1LG2 Antibody
(5N738)
(5N738)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-PDCD1LG2 Antibody (5N738) is a Mouse antibody targeting PDCD1LG2. Anti-PDCD1LG2 Antibody (5N738) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1, k |
| Clone | 5N738 |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of PDL-2 in untransfecteD (left) or transfecteD (right) with 293T cell sections. Cell was fixed with formaldehyde; antigen retrieval was by heat mediation with a EDTA buffer (pH9. 0). Samples were incubated with primary antibody (1: 25) for 1 hours at room temperature. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody. 2. Sample: Lane 1: Non-transfected 293T cell lysates Lane 2: Transfected PD-L2-transfected 293T cell lysates Primary: Anti-PDCD1LG2 (TMAB-10096) at 1/8000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 29 kD Observed band size: 40-55 kD |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC-P: 1:100-400; IHC-Fr: 1:100-400; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Isoform 3: Secreted (Probable). Isoform 2: Endomembrane system; Single-pass type I membrane protein. Isoform 1: Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | B7DC is a 33kDa member of the immunoglobulin receptor superfamily expressed on DC, liver and a small subset of macrophages as well as a few transformed cell lines. B7DC has been reported to be stimulatory on dendritic cells when cross linked and to inhibit T cell activation upon engaging the PD1 receptor. B7DC has also been reported to bind to an alternative receptor and to mediate T cell activation through non PD1 mediated interactions. |
| Immunogen | KLH conjugated synthetic peptide: human PDCD1LG2 |
| Antigen Species | Human |
| Gene Name | PDCD1LG2 |
| Gene ID | |
| Protein Name | Programmed cell death 1 ligand 2 |
| Uniprot ID | |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). |
| Molecular Weight | Theoretical: 29 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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