α4-α6

6-Bromo-4-nitro-1H-indazole ,with CAS No. 885518-46-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Bromo-4-nitro-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

GsMTx4 TFA (1209500-46-8 free base) is a spider venom peptide that selectively inhibits cation permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families.

Somatostatin 1-28 acetate circulates in human plasma. Approximately 46% of the total somatostatin-like immunoreactivity in plasma is due to Somatostatin 1-28 acetate.

Vaborbactam ammonium salt is a β-lactamase inhibitor that restores carbapenem activity against KPC-producing strains and is often used in conjunction with other drugs to study fungal infections.

(3R,6R)-Vaborbactam ((3R,6R)-Vaborbactam (Iso-1360457-46-0)) is a cyclic boronic acid pharmacophore β-lactamase inhibitor with potential antimicrobial activity. (S)-Vamicamide ((S)-Vamicamide (Iso-132373-81-0)) is a novel anticholinergic compound.

TG-46 (TG46) inhibits JAK2, FLT3, RET, JAK3 and can be used to study glaucoma.

VX-702 is a highly specific p38α MAPK inhibitor, 14-fold higher selectivity for the p38α than p38β. VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA).

RMM-46 is a reversible covalent inhibitor with high ligand efficiency and selectivity for MSK/RSK family kinases.

Deracoxib (SC 46) is a non-steroidal, non-narcotic anti-inflammatory drug. It is also a selective cyclooxygenase-2 inhibitor, and IC50 Value: 70 to 150 μM(inhibition of 3 osteosarcoma cell lines).

MCPA(Krezone) is a highly effective phenoxy herbicide. Use of MCPA would have impacts on nearby water and soil resources.

Anticancer agent 46 is a potent anti-cancer agent, showing anti-proliferative activity in cellular assays, with an IC50 of 0.986 μM against MGC803 cells.

6-Bromo-4-hydroxyquinolin-2(1H)-one ,with CAS No. 54675-23-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Bromo-4-hydroxyquinolin-2(1H)-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-(4-Chlorophenyl) glutarimide ,with CAS No. 84803-46-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-(4-Chlorophenyl) glutarimide provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Pindolol is an effective, non-selective, and specific beta-receptor blocker that acts as a partial beta-adrenergic receptor agonist and a localized 5-HT1A receptor antagonist (Ki=33nM). Pindolol has intrinsic sympathetic activity (ISA) and is primarily used to treat high blood pressure and certain heart conditions. Exhaustion.

Napsagatran hydrate is a novel and specific thrombin inhibitor.

DSPE-PEG46-DBCO is a PEG-based linker for PROTACs, connecting two essential ligands to form PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DSPE-PEG46-Folate is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DSPE-PEG46-N3, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DSPE-PEG46-NH2 is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1].

Antimalarial agent 46 (Compound 42a) is a compound with antimalarial activity, effective in inhibiting P. falciparum lines.

PRMT5-IN-46 (compound 278) is a PRMT5 inhibitor (IC50 = 1–10 μM) applicable for studying proliferative diseases, metabolic disorders, and hematological conditions.

E3 ligase Ligand 46 is a ligand of E3 ligase and is used in the synthesis of PROTAC SMARCA2/4 degrader-36.

Antiproliferative agent-46 is an inhibitor of the casein kinase 2 enzyme (CK2) receptor and exhibits potent antiproliferative activity, with an IC50 value of 5.75 μM against the U87 cell line.