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Anti-CREB3L4 Antibody (5F216)
😃Good
Catalog No. TMAB-04655
Anti-CREB3L4 Antibody (5F216) is a Mouse antibody targeting CREB3L4. Anti-CREB3L4 Antibody (5F216) can be used in WB.
Anti-CREB3L4 Antibody (5F216)
Anti-CREB3L4 Antibody (5F216)
😃Good
Catalog No. TMAB-04655
Anti-CREB3L4 Antibody (5F216) is a Mouse antibody targeting CREB3L4. Anti-CREB3L4 Antibody (5F216) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CREB3L4 Antibody (5F216) is a Mouse antibody targeting CREB3L4. Anti-CREB3L4 Antibody (5F216) can be used in WB. |
| Ig Type | IgG1 |
| Clone | 5F216 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus and Endoplasmic reticulum membrane. Golgi apparatus membrane. May also be located in Golgi apparatus. |
| Tissue Specificity | According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast and prostate cancer cell lines. Expressed in prostatic luminal epithelial cells (at protein level). Expression is significantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia). According to PubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine, testis, leukocyte and thymus. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| Immunogen | Recombinant Protein: human CREB3L4 between 1-300 amino acids |
| Antigen Species | Human |
| Gene Name | CREB3L4 |
| Gene ID | |
| Protein Name | Cyclic AMP-responsive element-binding protein 3-like protein 4 |
| Function | Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity). |
| Molecular Weight | Theoretical: 21 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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