Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-CXADR/CAR Antibody-FITC (7D440) is a FITC-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-FITC (7D440) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 T | $105 | 7-10 days | |
100 T | $211 | 7-10 days |
Description | Anti-CXADR/CAR Antibody-FITC (7D440) is a FITC-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-FITC (7D440) can be used in FCM. |
Alias | HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7D440 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of human CXADR expression on HT-29 cells. HT-29 cells were stained with FITC-conjugated anti-Human CXARD. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CXADR / CAR (rh CXADR / CAR; TMPY-02121; NP_001329.1; Met1-Gly237) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR. |
Conjucates | FITC |
Others Formats | Unconjugated/PE |
Antibody Types Available | 3 |
Immunogen | Recombinant Human CXADR / CAR protein (TMPY-02121) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.