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Anti-CXADR/CAR Antibody-FITC (7D440)

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Catalog No. TMAY-01175F
Alias HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR

Anti-CXADR/CAR Antibody-FITC (7D440) is a FITC-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-FITC (7D440) can be used in FCM.

Anti-CXADR/CAR Antibody-FITC (7D440)

Anti-CXADR/CAR Antibody-FITC (7D440)

😃Good
Catalog No. TMAY-01175FAlias HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR
Anti-CXADR/CAR Antibody-FITC (7D440) is a FITC-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-FITC (7D440) can be used in FCM.
Pack SizePriceAvailabilityQuantity
25 T$105 7-10 days
100 T$211 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CXADR/CAR Antibody-FITC (7D440) is a FITC-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-FITC (7D440) can be used in FCM.
AliasHCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR
Ig Type
Monoclonal Rabbit IgG
Clone
7D440
Reactivity
Human
Verified Activity
Flow cytometric analysis of human CXADR expression on HT-29 cells. HT-29 cells were stained with FITC-conjugated anti-Human CXARD. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CXADR / CAR (rh CXADR / CAR; TMPY-02121; NP_001329.1; Met1-Gly237) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundCXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR.
Related Conjugates and Formulations
Conjucates
FITC
Others Formats
Unconjugated/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human CXADR / CAR protein (TMPY-02121)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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