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Anti-CD289 Monoclonal Antibody (5S467)

(Synonyms: TLR9) Copy Product Info
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Synonyms: TLR9

Catalog No. TMAT-0356 Copy Product Info
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Anti-CD289 Monoclonal Antibody (5S467) is a Mouse antibody targeting CD289. Anti-CD289 Monoclonal Antibody (5S467) can be used in FCM.

Anti-CD289 Monoclonal Antibody
(5S467)

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Product Introduction

Bioactivity
Description
Anti-CD289 Monoclonal Antibody (5S467) is a Mouse antibody targeting CD289. Anti-CD289 Monoclonal Antibody (5S467) can be used in FCM.
SynonymsTLR9
Ig Type
IgG1
Clone
5S467
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CD289 (AA: extra 26-193) expressed in E. Coli.
Antigen Species
Human
Gene Name
TLR9
Gene ID
Protein Name
Toll-like receptor 9
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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