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Synonyms: TLR9
Anti-CD289 Monoclonal Antibody
(5S467)

| Description | Anti-CD289 Monoclonal Antibody (5S467) is a Mouse antibody targeting CD289. Anti-CD289 Monoclonal Antibody (5S467) can be used in FCM. |
| Synonyms | TLR9 |
| Ig Type | IgG1 |
| Clone | 5S467 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD289 (AA: extra 26-193) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TLR9 |
| Gene ID | |
| Protein Name | Toll-like receptor 9 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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