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Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546)
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Catalog No. TMAY-00002
Alias Ighg1, IgG1 Fc
Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546) is a Mouse antibody targeting IgG1 Fc. Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546) can be used in ELISA.
Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546)
Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546)
😃Good
Catalog No. TMAY-00002Alias Ighg1, IgG1 Fc
Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546) is a Mouse antibody targeting IgG1 Fc. Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $94 | 7-10 days | |
| 100 μL | $188 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546) is a Mouse antibody targeting IgG1 Fc. Mouse Anti-Human IgG1-Fc Secondary Antibody (2V546) can be used in ELISA. |
| Alias | Ighg1, IgG1 Fc |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2V546 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS with 0.02% Tween 80, pH 7.0 |
| Research Background | As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (5 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. Protein G or Protein A on the surface of certain Staphylococcal and Streptococcal strains specifically binds with the Fc region of IgGs, and has numerous applications in biotechnology as a reagent for affinity purification. Recombinant IgG Fc Region is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases. |
| Conjucates | Unconjugated |
| Others Formats | HRP |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human IgG1-Fc Protein (TMPY-00820) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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