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Anti-J chain Antibody (7E468)

😃Good
Catalog No. TMAY-02432
Alias JCH, immunoglobulin joining chain, IGCJ

Anti-J chain Antibody (7E468) is a Rabbit antibody targeting J chain. Anti-J chain Antibody (7E468) can be used in ELISA.

Anti-J chain Antibody (7E468)

Anti-J chain Antibody (7E468)

😃Good
Catalog No. TMAY-02432Alias JCH, immunoglobulin joining chain, IGCJ
Anti-J chain Antibody (7E468) is a Rabbit antibody targeting J chain. Anti-J chain Antibody (7E468) can be used in ELISA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
20 μL$937-10 days7-10 days
100 μL$2697-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-J chain Antibody (7E468) is a Rabbit antibody targeting J chain. Anti-J chain Antibody (7E468) can be used in ELISA.
SynonymsJCH, immunoglobulin joining chain, IGCJ
Ig Type
Rabbit IgG
Clone
7E468
Reactivity
Human
Specificity
Human J chain
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human IGJ (TMPY-01918; NP_653247.1; Gln23-Asp159).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundImmunoglobulin J chain, also known as IGJ and IGCJ, is a secreted polypeptide which is the first immunoglobulin-related polypeptide expressed during the embryogenesis and differentiation of B cells in the fetal liver. The joining Immunoglobulin J chain is a small polypeptide, expressed by mucosal and glandular plasma cells, which regulates polymer formation of immunoglobulin (Ig)A and IgM. Immunoglobulin J chain / IGJ serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA, it induces larger polymers. Immunoglobulin J chain / IGJ also helps to bind these immunoglobulins to the secretory component. J-chain incorporation into polymeric IgA (pIgA, mainly dimers) and pentameric IgM endows these antibodies with several salient features. Immunoglobulin J chain / IGJ is involved in creating the binding site for pIgR / SC in the Ig polymers, not only by determining the polymeric quaternary structure but also by interacting directly with the receptor protein. Both the immunoglobulin J chain / IGJ and the pIgR/SC are key proteins in secretory immunity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IGJ protein (TMPY-01918)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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