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Anti-J chain Antibody (7E468)
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Catalog No. TMAY-02432
Alias JCH, immunoglobulin joining chain, IGCJ
Anti-J chain Antibody (7E468) is a Rabbit antibody targeting J chain. Anti-J chain Antibody (7E468) can be used in ELISA.
Anti-J chain Antibody (7E468)
Anti-J chain Antibody (7E468)
😃Good
Catalog No. TMAY-02432Alias JCH, immunoglobulin joining chain, IGCJ
Anti-J chain Antibody (7E468) is a Rabbit antibody targeting J chain. Anti-J chain Antibody (7E468) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $93 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-J chain Antibody (7E468) is a Rabbit antibody targeting J chain. Anti-J chain Antibody (7E468) can be used in ELISA. |
| Alias | JCH, immunoglobulin joining chain, IGCJ |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7E468 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human IGJ (TMPY-01918; NP_653247.1; Gln23-Asp159). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Immunoglobulin J chain, also known as IGJ and IGCJ, is a secreted polypeptide which is the first immunoglobulin-related polypeptide expressed during the embryogenesis and differentiation of B cells in the fetal liver. The joining Immunoglobulin J chain is a small polypeptide, expressed by mucosal and glandular plasma cells, which regulates polymer formation of immunoglobulin (Ig)A and IgM. Immunoglobulin J chain / IGJ serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA, it induces larger polymers. Immunoglobulin J chain / IGJ also helps to bind these immunoglobulins to the secretory component. J-chain incorporation into polymeric IgA (pIgA, mainly dimers) and pentameric IgM endows these antibodies with several salient features. Immunoglobulin J chain / IGJ is involved in creating the binding site for pIgR / SC in the Ig polymers, not only by determining the polymeric quaternary structure but also by interacting directly with the receptor protein. Both the immunoglobulin J chain / IGJ and the pIgR/SC are key proteins in secretory immunity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IGJ protein (TMPY-01918) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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