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TCS 46b

Name: TCS 46b
Brand: TargetMol
SKU: T23449
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T23449Cas No. 302799-86-6

TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.

TCS 46b

🥰Excellent

Purity: 99.78%

Catalog No. T23449Cas No. 302799-86-6

TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.

Pack Size	Price	Availability
2 mg	$39	In Stock
5 mg	$65	In Stock
10 mg	$106	In Stock
25 mg	$223	In Stock
50 mg	$358	In Stock
100 mg	$592	In Stock
200 mg	$783	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.78%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.

Chemical Properties

Molecular Weight	345.44
Formula	C₂₂H₂₃N₃O
Cas No.	302799-86-6
Smiles	C(#CCN1CCC(CC2=CC=CC=C2)CC1)C=3C=C4C(=CC3)NC(=O)N4
Relative Density.	1.24 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (159.22 mM), Sonication is recommended.

Ethanol: < 34.54 mg/mL, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8949 mL	14.4743 mL	28.9486 mL	144.7429 mL
5 mM	0.5790 mL	2.8949 mL	5.7897 mL	28.9486 mL
10 mM	0.2895 mL	1.4474 mL	2.8949 mL	14.4743 mL
20 mM	0.1447 mL	0.7237 mL	1.4474 mL	7.2371 mL
50 mM	0.0579 mL	0.2895 mL	0.5790 mL	2.8949 mL
100 mM	0.0289 mL	0.1447 mL	0.2895 mL	1.4474 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc