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Anti-Leukotriene A4 Hydrolase Antibody (2M416) (Synonyms: Lta4h, leukotriene A4 hydrolase)

Catalog No. TMAY-00546 Copy Product Info
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Anti-Leukotriene A4 Hydrolase Antibody (2M416) is a Rabbit antibody targeting Leukotriene A4 Hydrolase. Anti-Leukotriene A4 Hydrolase Antibody (2M416) can be used in ELISA.

Anti-Leukotriene A4 Hydrolase Antibody (2M416)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00546
Synonyms Lta4h, leukotriene A4 hydrolase

Anti-Leukotriene A4 Hydrolase Antibody (2M416) is a Rabbit antibody targeting Leukotriene A4 Hydrolase. Anti-Leukotriene A4 Hydrolase Antibody (2M416) can be used in ELISA.

Anti-Leukotriene A4 Hydrolase Antibody
(2M416)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Leukotriene A4 Hydrolase Antibody (2M416) is a Rabbit antibody targeting Leukotriene A4 Hydrolase. Anti-Leukotriene A4 Hydrolase Antibody (2M416) can be used in ELISA.
SynonymsLta4h, leukotriene A4 hydrolase
Ig Type
Rabbit IgG
Clone
2M416
Reactivity
Human
Specificity
Human Leukotriene A4 Hydrolase
Has cross-reactivity in ELISA with
Mouse LTA4H
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Leukotriene A4 Hydrolase / LTA4H (rh Leukotriene A4 Hydrolase / LTA4H; TMPY-00877; NP_000886.1; Met 1-Asp 611).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLeukotriene A-4 hydrolase, also known as LTA-4 hydrolase, Leukotriene A (4) hydrolase, LTA4H, and LTA4, is a cytoplasm protein that belongs to the peptidase M1 family. LTA4H hydrolyzes an epoxide moiety of leukotriene A4 (LTA-4) to form leukotriene B4 (LTB-4). This enzyme also has some peptidase activity. The leukotrienes (LTs) are a class of structurally related lipid mediators involved in the development and maintenance of inflammatory and allergic reactions. In the biosynthesis of LTs, arachidonic acid was converted into the unstable intermediate epoxide LTA4, which may, in turn, be conjugated with glutathione to form the spasmogenic LTC4, or hydrolyzed into the pro-inflammatory lipid mediator LTB4 in a reaction catalyzed by Leukotriene A4 hydrolase (LTA4H). LTB4 is a classical chemoattractant of human neutrophils and triggers adherence and aggregation of leukocytes to vascular endothelium, and also modulates immune responses. As a bifunctional zinc metalloenzyme, LTA4H also exhibits an anion-dependant arginyl aminopeptidase activity of high efficiency and specificity in addition to its epoxide hydrolase activity. LTA4H is regarded as a therapeutic target for inflammation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human Leukotriene A4 Hydrolase / LTA4H protein (TMPY-00877)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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