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Anti-Kallikrein 8/KLK8 Antibody (2Q646) (Synonyms: TADG14, PRSS19, NRPN, NP, kallikrein-related peptidase 8|...)

Catalog No. TMAY-02067 Copy Product Info
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Anti-Kallikrein 8/KLK8 Antibody (2Q646) is a Rabbit antibody targeting Kallikrein 8/KLK8. Anti-Kallikrein 8/KLK8 Antibody (2Q646) can be used in ELISA.

Anti-Kallikrein 8/KLK8 Antibody (2Q646)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02067
Synonyms TADG14, PRSS19, NRPN, NP, kallikrein-related peptidase 8, HNP

Anti-Kallikrein 8/KLK8 Antibody (2Q646) is a Rabbit antibody targeting Kallikrein 8/KLK8. Anti-Kallikrein 8/KLK8 Antibody (2Q646) can be used in ELISA.

Anti-Kallikrein 8/KLK8 Antibody
(2Q646)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Kallikrein 8/KLK8 Antibody (2Q646) is a Rabbit antibody targeting Kallikrein 8/KLK8. Anti-Kallikrein 8/KLK8 Antibody (2Q646) can be used in ELISA.
SynonymsTADG14, PRSS19, NRPN, NP, kallikrein-related peptidase 8, HNP
Ig Type
Rabbit IgG
Clone
2Q646
Reactivity
Human
Specificity
Human Kallikrein 8/Neuropsin
No cross-reactivity in ELISA with
Human KLK1
Human KLK3
Human KLK4
Human KLK7
Human KLK11
Human HGFA
Mouse FVII
Human FX
Human FA11
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human KLK8 / Kallikrein 8 (rh KLK8 / Kallikrein 8; TMPY-01992; O60259-1; Met1-Gly260).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundKallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. It is a serine protease that is capable of degrading some proteins such as casein, fibrinogen, kininogen, fibronectin, and collagen type IV. Kallikrein-8 / KLK8 plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway. It regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. It is involved in skin desquamation and keratinocyte proliferation and plays a role in the secondary phase of pathogenesis following spinal cord injury. It also cleaves L1CAM in response to increased neural activity. It induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Kallikrein-8 / KLK8 is expressed at high levels in serum, ascites fluid, and tumor cytosol of advanced-stage ovarian cancer patients and may serve as a marker of ovarian cancer. Kallikrein-8 / KLK8 may have potential clinical value for disease diagnosis or prognosis and it may also be a useful therapeutic target.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human KLK8 / Kallikrein 8 protein (TMPY-01992)
Antigen Species
Human
Biology Area
Serine Proteases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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