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11(Z),14(Z)-Eicosadienoic acid

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Catalog No. T84631Cas No. 5598-38-9

11(Z),14(Z)-Eicosadienoic acid is an unsaturated fatty acid and metabolite that inhibits the binding of [3H]LTB4 to neutrophil modules (Ki=3 μm).

11(Z),14(Z)-Eicosadienoic acid

11(Z),14(Z)-Eicosadienoic acid

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Purity: 99.94%
Catalog No. T84631Cas No. 5598-38-9
11(Z),14(Z)-Eicosadienoic acid is an unsaturated fatty acid and metabolite that inhibits the binding of [3H]LTB4 to neutrophil modules (Ki=3 μm).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30-In Stock
25 mg$44-In Stock
50 mg$71-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.94%
Appearance:Liquid
Color:Yellow
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Product Introduction

Bioactivity
Description
11(Z),14(Z)-Eicosadienoic acid is an unsaturated fatty acid and metabolite that inhibits the binding of [3H]LTB4 to neutrophil modules (Ki=3 μm).
In vitro
11(Z),14(Z)-Eicosadienoic acid inhibits the binding of radiolabeled leukotriene B4 (\[³H]-LTB4) to porcine neutrophil membranes with a Ki of 3 μM, indicating its potential anti-inflammatory activity[1].
Chemical Properties
Molecular Weight308.5
FormulaC20H36O2
Cas No.5598-38-9
SmilesC(CC/C=C\C/C=C\CCCCC)CCCCCCC(O)=O
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 80 mg/mL (259.32 mM), Sonication is recommended.
DMSO: 100 mg/mL (324.15 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.2415 mL16.2075 mL32.4149 mL162.0746 mL
5 mM0.6483 mL3.2415 mL6.4830 mL32.4149 mL
10 mM0.3241 mL1.6207 mL3.2415 mL16.2075 mL
20 mM0.1621 mL0.8104 mL1.6207 mL8.1037 mL
50 mM0.0648 mL0.3241 mL0.6483 mL3.2415 mL
100 mM0.0324 mL0.1621 mL0.3241 mL1.6207 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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