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Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442)
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Catalog No. TMAY-02914
Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) is a Chimera antibody targeting Influenza A H10N8 Hemagglutinin/HA. Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) can be used in HemagglutininInhibition(HI).
Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442)
Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442)
😃Good
Catalog No. TMAY-02914
Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) is a Chimera antibody targeting Influenza A H10N8 Hemagglutinin/HA. Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) can be used in HemagglutininInhibition(HI).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 200 μg | $234 | 7-10 days | |
| 500 μg | $352 | 7-10 days |
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Related Conjugates and Formulations
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Chemical Properties
| Description | Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) is a Chimera antibody targeting Influenza A H10N8 Hemagglutinin/HA. Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) can be used in HemagglutininInhibition(HI). |
| Ig Type | Monoclonal mouse (varialbe region) / human (kappa / IgG1 constant) chimeric antibody |
| Clone | 5E442 |
| Verified Activity | The neutralization activity of H10N8 HA protein antibody is Measured by Microneutralization test in vitro.The pseudovirus microneutralizaiton (MN) test was performed on 293FT cells infected with H10N8 (A/Jiangxi-Donghu/346/2013) pseudovirus under the treatment of serial dilution of Neutralizing Antibody. The inhibition is 99.3% under 1 μg/mL influenza A H10N8 HA Neutralizing Antibody with high titer H10N8 pseduotype virus. |
| Application | HemagglutininInhibition(HI) |
| Antibody Type | Monoclonal |
| Host Species | Chimera |
| Construction | It is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified, recombinant Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin / HA. The antibody was produced using recombinant antibody technology. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin / HA protein (TMPY-02662) |
| Antigen Species | H10N8 |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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