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Anti-MUSK Monoclonal Antibody (7C469)
(Synonyms: FADS, CMS9) Copy Product Info
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Synonyms: FADS, CMS9
Catalog No. TMAT-0554 Copy Product Info
🥰Excellent
Anti-MUSK Monoclonal Antibody (7C469) is a Mouse antibody targeting MUSK. Anti-MUSK Monoclonal Antibody (7C469) can be used in IHC,IF.
Anti-MUSK Monoclonal Antibody
(7C469)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-MUSK Monoclonal Antibody (7C469) is a Mouse antibody targeting MUSK. Anti-MUSK Monoclonal Antibody (7C469) can be used in IHC,IF. |
| Synonyms | FADS, CMS9 |
| Ig Type | IgG1 |
| Clone | 7C469 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | MuSK (for Muscle Specific Kinase) is a receptor tyrosine kinase required for the formation of the neuromuscular junction (NMJ). It induces cellular signaling by causing the addition of phosphate molecules to particular tyrosines on itself, and on proteins which bind the cytoplasmic domain of the receptor. It is activated by a nerve-derived proteoglycan called agrin. During development, the growing end of motor neuron axons secrete a protein called agrin.This protein binds to several receptors on the surface of skeletal muscle. The receptor which seems to be required for formation of the neuromuscular junction (NMJ), which comprises the nerve-muscle synapse is called MuSK. MUSK mutations lead to decreased agrin-dependent AchR aggregation, a critical step in the formation of the neuromuscular junction. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human MUSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line. |
| Antigen Species | Human |
| Gene Name | MUSK |
| Gene ID | |
| Protein Name | Muscle, skeletal receptor tyrosine-protein kinase |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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