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Anti-KRT5 Antibody (5H465) (Synonyms: KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1||...)

Catalog No. TMAY-00122 Copy Product Info
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Anti-KRT5 Antibody (5H465) is a Mouse antibody targeting KRT5. Anti-KRT5 Antibody (5H465) can be used in WB.

Anti-KRT5 Antibody (5H465)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00122
Synonyms KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5

Anti-KRT5 Antibody (5H465) is a Mouse antibody targeting KRT5. Anti-KRT5 Antibody (5H465) can be used in WB.

Anti-KRT5 Antibody
(5H465)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-KRT5 Antibody (5H465) is a Mouse antibody targeting KRT5. Anti-KRT5 Antibody (5H465) can be used in WB.
SynonymsKRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5
Ig Type
Mouse IgG1
Clone
5H465
Reactivity
Human
Specificity
Human Cytokeratin 5/KRT5
Verified Activity
Anti-KRT5 mouse monoclonal antibody at 1:500 dilution.
-Lane A: A431 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:62 kDa.
-Observed band size:62 kDa
Application
Recommended Dose
WB: 1:500-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the center region of the human KRT5. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundKeratin 5 is the major type II keratin of the basal cells of the epidermis and other stratified epithelia. With its type I partner, keratin 14, it constitutes a major fraction of the cytoskeleton of the basal cells. Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a rare dermatologic disorder of autosomal dominant inheritance with intraepidermal blistering after minor trauma, reticular hyperpigmentation unrelated to the blistering, nail dystrophy, and mild palmoplantar keratosis. Keratin 5 and keratin 14 are known to be essential for the basal keratinocyte cytoskeleton and are defective in several forms of epidermolysis bullosa simplex. Recently, a 71C-->T transition in the keratin 5 gene (KRT5) causing a P24L substitution was identified in some patients with EBS-MP.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: center region of the human KRT5
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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