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Anti-CD86 Antibody (4G469) (Synonyms: LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2)

Name: Anti-CD86 Antibody (4G469)
Brand: TargetMol
SKU: TMAY-01082
Rating: 4.5 (1 reviews)

Catalog No. TMAY-01082 Copy Product Info

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Anti-CD86 Antibody (4G469) is a Mouse antibody targeting CD86. Anti-CD86 Antibody (4G469) can be used in ELISA.

Anti-CD86 Antibody (4G469)

Copy Product Info

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Catalog No. TMAY-01082

Synonyms LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2

Anti-CD86 Antibody (4G469) is a Mouse antibody targeting CD86. Anti-CD86 Antibody (4G469) can be used in ELISA.

Anti-CD86 Antibody
(4G469)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$198	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-CD86 Antibody (4G469) is a Mouse antibody targeting CD86. Anti-CD86 Antibody (4G469) can be used in ELISA.
Synonyms	LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Ig Type	Mouse IgG1
Clone	4G469
Reactivity	Human
Specificity	Human B7-2/CD86 No cross-reactivity in ELISA with Mouse CD86 / B7-2 / B70 Human CD80 / B7-1 / CD28LG Human CD274 / B7-H1 / PD-L1 Human cell lysate (293 cell line)
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD86 / B7-2 (rh CD86; TMPY-01180; NP_008820.2; Met 1-His 239). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human CD86 protein (TMPY-01180)
Antigen Species	Human
Biology Area	Cancer Drug Targets

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

LAB-72LAB 72B-70B 70

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