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Anti-PU.1/Spi1 Antibody (7E746)
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Catalog No. TMAB-11941
Anti-PU.1/Spi1 Antibody (7E746) is a Mouse antibody targeting PU.1/Spi1. Anti-PU.1/Spi1 Antibody (7E746) can be used in WB.
Anti-PU.1/Spi1 Antibody (7E746)
Anti-PU.1/Spi1 Antibody (7E746)
😃Good
Catalog No. TMAB-11941
Anti-PU.1/Spi1 Antibody (7E746) is a Mouse antibody targeting PU.1/Spi1. Anti-PU.1/Spi1 Antibody (7E746) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PU.1/Spi1 Antibody (7E746) is a Mouse antibody targeting PU.1/Spi1. Anti-PU.1/Spi1 Antibody (7E746) can be used in WB. |
| Ig Type | IgG1, k |
| Clone | 7E746 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008] |
| Immunogen | Recombinant Protein: human SPI1 |
| Antigen Species | Human |
| Gene Name | SPI1 |
| Gene ID | |
| Protein Name | Transcription factor PU.1 |
| Uniprot ID | |
| Function | Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. |
| Molecular Weight | Theoretical: 31 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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