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Anti-CD84 Antibody (4Q464) (Synonyms: CD84 molecule)

Catalog No. TMAY-00253 Copy Product Info
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Anti-CD84 Antibody (4Q464) is a Mouse antibody targeting CD84. Anti-CD84 Antibody (4Q464) can be used in ELISA(Det).

Anti-CD84 Antibody (4Q464)

Copy Product Info
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Catalog No. TMAY-00253
Synonyms CD84 molecule

Anti-CD84 Antibody (4Q464) is a Mouse antibody targeting CD84. Anti-CD84 Antibody (4Q464) can be used in ELISA(Det).

Anti-CD84 Antibody
(4Q464)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$697-10 days7-10 days
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD84 Antibody (4Q464) is a Mouse antibody targeting CD84. Anti-CD84 Antibody (4Q464) can be used in ELISA(Det).
SynonymsCD84 molecule
Ig Type
Mouse IgG1
Clone
4Q464
Reactivity
Human
Specificity
Human CD84
Application
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD84 (rh CD84; TMPY-00715; NP_003865.1; Met1-Gly225). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CD84 Protein (TMPY-00715)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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