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Anti-VEGF Antibody
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Catalog No. T9901A-1469 Copy Product Info
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Anti-VEGF Antibody is a neutralizing monoclonal antibody targeting vascular endothelial growth factor (VEGF). It inhibits endothelial cell proliferation and neo-angiogenesis by binding to free VEGF and preventing receptor interaction, widely used in research on solid tumors and vasoproliferative eye diseases.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-VEGF Antibody is a neutralizing monoclonal antibody targeting vascular endothelial growth factor (VEGF). It inhibits endothelial cell proliferation and neo-angiogenesis by binding to free VEGF and preventing receptor interaction, widely used in research on solid tumors and vasoproliferative eye diseases. |
| In vitro | Anti-VEGF Antibody dose-dependently inhibits VEGF-induced HUVEC proliferation by effectively neutralizing multiple VEGF isoforms and blocking downstream MAPK and PI3K/Akt signaling pathways [1]. |
| In vivo | In tumor xenograft models, systemic administration of Anti-VEGF Antibody resulted in a significant reduction in microvessel density and marked tumor growth inhibition across multiple cancer types. The treatment was shown to decrease interstitial fluid pressure and improve the delivery of co-administered chemotherapeutic agents by normalizing the tumor vasculature [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | VEGF |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Anti-VEGF Antibody chemical structure | Anti-VEGF Antibody in vivo | Anti-VEGF Antibody in vitro
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