Shopping Cart

Remove All
Your shopping cart is currently empty

BMS-564929

Name: BMS-564929
Brand: TargetMol
SKU: T14675
Price: 149 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T14675Cas No. 627530-84-1

Alias BMS564929

BMS-564929 is a highly effective androgen receptor (AR) agonist that upregulates the expression and activity of lipogenic enzymes, reduces VAT content and lipid content, and downregulates the expression of acetyl-CoA carboxylase, FASN, and SCD.

BMS-564929

🥰Excellent

Purity: 98.17%

Catalog No. T14675Alias BMS564929Cas No. 627530-84-1

Pack Size	Price	Availability	Quantity
2 mg	$149	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.17%

Resource Download

COA

Product Introduction

Bioactivity

Description	BMS-564929 is a highly effective androgen receptor (AR) agonist that upregulates the expression and activity of lipogenic enzymes, reduces VAT content and lipid content, and downregulates the expression of acetyl-CoA carboxylase, FASN, and SCD.
Targets&IC50	AR:2.11 nM (Ki)
In vitro	BMS-564929 is a novel, highly effective and orally active non-steroidal tissue-selective androgen receptor (AR) modulator with Ki = 2.11 nM. The EC50 value of BMS-564929 in mouse myoblasts (C2C12) and rat PEC cell lines was 0.44 nM and 8.66 nM, respectively. [1]
In vivo	BMS-564929 (0.00001 - 10 mg/kg,14 days, gavage) is more effective than testosterone in stimulating the growth of the levator anal muscle and has a strong oral activity. [1]
Synonyms	BMS564929

Chemical Properties

Molecular Weight	305.72
Formula	C₁₄H₁₂ClN₃O₃
Cas No.	627530-84-1
Smiles	O=C1N(C(=O)N2[C@]1([C@H](O)CC2)[H])C3=C(C)C(Cl)=C(C#N)C=C3
Relative Density.	1.58 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 40 mg/mL (130.84 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.54 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2710 mL	16.3548 mL	32.7097 mL	163.5483 mL
5 mM	0.6542 mL	3.2710 mL	6.5419 mL	32.7097 mL
10 mM	0.3271 mL	1.6355 mL	3.2710 mL	16.3548 mL
20 mM	0.1635 mL	0.8177 mL	1.6355 mL	8.1774 mL
50 mM	0.0654 mL	0.3271 mL	0.6542 mL	3.2710 mL
100 mM	0.0327 mL	0.1635 mL	0.3271 mL	1.6355 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc