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Synonyms: HNUC, D17S978E, D0S1430E, CDC27Hs, APC3, ANAPC3
Anti-CDC27 Monoclonal Antibody
(6B30)

| Description | Anti-CDC27 Monoclonal Antibody (6B30) is a Mouse antibody targeting CDC27. Anti-CDC27 Monoclonal Antibody (6B30) can be used in IHC. |
| Synonyms | HNUC, D17S978E, D0S1430E, CDC27Hs, APC3, ANAPC3 |
| Ig Type | IgG1 |
| Clone | 6B30 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CDC27 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CDC27 |
| Gene ID | |
| Protein Name | Cell division cycle protein 27 homolog |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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