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Anti-CDC27 Monoclonal Antibody (6B30)

(Synonyms: HNUC, D17S978E, D0S1430E, CDC27Hs, APC3, ANAPC3) Copy Product Info
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Synonyms: HNUC, D17S978E, D0S1430E, CDC27Hs, APC3, ANAPC3

Catalog No. TMAT-0467 Copy Product Info
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Anti-CDC27 Monoclonal Antibody (6B30) is a Mouse antibody targeting CDC27. Anti-CDC27 Monoclonal Antibody (6B30) can be used in IHC.

Anti-CDC27 Monoclonal Antibody
(6B30)

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Product Introduction

Bioactivity
Description
Anti-CDC27 Monoclonal Antibody (6B30) is a Mouse antibody targeting CDC27. Anti-CDC27 Monoclonal Antibody (6B30) can be used in IHC.
SynonymsHNUC, D17S978E, D0S1430E, CDC27Hs, APC3, ANAPC3
Ig Type
IgG1
Clone
6B30
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationAscitic fluid containing 0.03% sodium azide
Concentration1 mg/ml
Research BackgroundCdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CDC27 expressed in E. Coli.
Antigen Species
Human
Gene Name
CDC27
Gene ID
Protein Name
Cell division cycle protein 27 homolog
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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