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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11857 | LIT-001 | Oxytocin Receptor | |
LIT-001 improves social interaction in a mouse model of autism.It is the first nonpeptide oxytocin receptor agonist with EC50 of 55 nM and Ki of 226 nM. | |||
T5207 | LIT927 | LIT 927,LIT-927 | CXCR |
LIT927 (LIT-927) is an orally active CXCL12 neutraligand (Ki: 267 nM for CXCL12 binding to CXCR4). | |||
T11856 | LIT-001 free base | Others | |
LIT-001 free base improves social interaction in a mouse model of autism. LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). | |||
T2331 | Solithromycin | OP-1068,CEM-101 | Antibacterial , Antibiotic |
Solithromycin (OP-1068) is an orally bioavailable antimicrobial agent that inhibits cell viability, protein synthesis, and growth rate of Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus aureus, and Haemop... | |||
T18885 | 3,6-Dichlorotrimellitic acid | Others | |
3,6-Dichlorotrimellitic acid serves as the fundamental precursor for the synthesis of numerous dichlorinated fluoresceins and rhodamines. | |||
T12400 | Peliglitazar racemate | (Rac)-Peliglitazar,(Rac)-BMS 426707-01,BMS 426707-01 racemate | PPAR |
Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesity agent. | |||
T12834 | Saroglitazar Magnesium | Others | |
Saroglitazar Magnesium is a novel peroxissome proliferator-activated receptor (PPAR) agonist with significant activation activity against PPARα (EC50 0.65pM) and moderate activation against PPARγ (EC50 3 nM). | |||
T12835 | Saroglitazar | Lipaglyn | PPAR |
Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ. | |||
T15575 | Indeglitazar | PPM 204 | PPAR |
Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)). | |||
T38404 | MJ33 lithium salt | ROS | |
MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, a fluorinated phospholipid analog that inhibits the phospholipase A2 (PLA2) activity of peroxiredoxin 6 (Prdx6), and is used in the study... | |||
T14336 | Allitinib | AST-1306,ALS 1306 | EGFR |
Allitinib (AST-1306) (AST-1306) has anti-cancer activity,and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1] | |||
T9702 | Eclitasertib | RIP kinase | |
Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ). | |||
TQ0210 | Savolitinib | AZD-6094,Volitinib,HMPL-504 | c-Met/HGFR |
Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met). | |||
T22708 | Darglitazone | CP-86325 | PPAR |
Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism. | |||
T14176 | Aleglitazar | RO0728804,R1439 | PPAR |
Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes. | |||
T20864 | 7-Troc-paclitaxel | Others | |
7-Troc-paclitaxel is a precursor of paclitaxel which has anti-tumor activity. | |||
T15581 | Inolitazone | RS5444,Efatutazone,CS-7017 | PPAR |
Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro. | |||
T15567 | Imiglitazar | TAK-559 | PPAR |
Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects. | |||
T33647L | Nesosteine Lithium | Nesosteine Lithium(84233-61-4 Free baes) | |
Nesosteine Lithium is a novel mucoregulatory that inhibits Herxheimer microconvulsions in guinea pigs and inhibits ovalbumin-induced histamine release from sensitized trachea.Nesosteine Lithium protects against ovalbumin... | |||
TP1299L | Melittin TFA(20449-79-0(free base)) | Phospholipase | |
Melittin TFA is a small protein containing 26 amino acid residues, is the principal toxic component of bee venom. Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not ... | |||
T67956L | Litoxetine HCl | litoxetine HCL(86811-09-8 Free base) | 5-HT Receptor |
Litoxetine HCl is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor (SSRI) and mixed 5-hydroxytryptamine antagonist used in the treatment of urinary incontinence. Litoxetine HCl in the absence of antimuscarinic c... | |||
T6646 | Rosiglitazone hydrochloride | BRL-49653 HCl,Rosiglitazone HCl | Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy |
Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells. | |||
T67956 | Litoxetine | 5-HT Receptor | |
Litoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently r... | |||
T19710 | Ciglitazone | Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878 | Apoptosis , p38 MAPK , PPAR |
Ciglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent. Ciglitazone inhibits proliferation and differentiation of th17 cells, decreases insulin levels, vascular endothelia... | |||
T4235 | Roblitinib | FGF-401 | FGFR |
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ... | |||
T9901A-002 | Enoblituzumab | MGA271,TJ-271 | Others |
Enoblituzumab is a humanized IgG1 κmab monoclonal antibody that recognizes human B7-H3 protein and can be used to study solid tumors such as non-small cell lung cancer (NSCLC). | |||
T6331 | Allitinib tosylate | AST-1306 TsOH,AST-6,Allitinib,AST-1306,AST-1306 (TsOH) | EGFR , FLT |
Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively. | |||
T4639 | Azemiglitazone | MSDC 0602 | Mitochondrial Metabolism , mTOR |
Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes. | |||
T26986 | Cevoglitazar | LBM-642,LBM 642,LBM642 | PPAR |
Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys. | |||
T27303 | Farglitazar | GI-262570,GI-2570,GW 262570X,GI 262570,GI262570 | PPAR |
Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer that inhibits stellate cell activation by activating receptor γ via oxidative enzymes proliferators and is used in the study of diabetes. | |||
T18886 | 3,6-Dichlorotrimellitic anhydride | Others | |
3,6-Dichlorotrimellitic anhydride serves as the essential precursor in the synthesis of various dichlorinated fluoresceins and rhodamines. | |||
T64334 | Glycolithocholic acid, sodium salt | Others | |
Glycolithocholic acid sodium salt, the sodium form of Glycolithocholic acid, is a glycine-conjugated secondary bile acid utilized in diagnosing ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH), and primary s... | |||
T21587 | Muraglitazar | Pargluva,BMS-298585 | PPAR |
Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitro at human PPARα and PPARγ with EC50 of 320 nM and 110 nM r... | |||
T16045 | Methotrexate metabolite | DAMPA | Antifolate , Drug Metabolite |
Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant. | |||
T10814 | Cinacalcet metabolite M4 | Rarechem AL BW 1078 | Calcium Channel |
Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor. | |||
T0334 | Rosiglitazone | BRL49653 | Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy |
Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer. | |||
T4274 | Melitracen hydrochloride | Thymeol hydrochloride,Melixeran | Dopamine Receptor , 5-HT Receptor |
Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression. | |||
T21059 | Ticagrelor metabolite M5 | Ticagrelor metabolite M5,,T437700,AR-C133913XX | P2Y Receptor |
Ticagrelor metabolite M5 (T437700) is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor. Compared to Clopidogrel, Ticagrelor has faster and more consistent inhibition on ADP-receptors. Ti... | |||
T0214 | Pioglitazone | U 72107 | Ferroptosis , PPAR |
Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury. | |||
T1622 | Rosiglitazone maleate | BRL 49653C,BRL 49653 | Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy |
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. | |||
T28743 | Seglitide acetate | MK 678,MK678,MK-678 | Somatostatin |
Seglitide acetate (MK-678) is a selective agonist of sst2 somatostatin receptor. | |||
T0214L | Pioglitazone hydrochloride | U-72107E,AD 4833,U 72107A,Pioglitazone HCl | Ferroptosis , PPAR |
Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. | |||
T12309 | Omeprazole metabolite Omeprazole sulfone | Omeprazole sulphone,Omeprazole sulfone | Others |
Omeprazole metabolite Omeprazole sulfone can inhibit proton pump. | |||
T2327 | Pelitinib | EKB-569,WAY-EKB 569 | EGFR , Raf , MEK , Src |
Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM). | |||
T28503 | Ralitoline | GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum | |
Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity. | |||
T1829 | Ruxolitinib | INCB018424,(R)-Ruxolitinib | Apoptosis , Mitophagy , Tyrosine Kinases , JAK , Autophagy |
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis. | |||
T7435 | Selitrectinib | LOXO-195 | Trk receptor |
Selitrectinib (LOXO-195) is a potent and selective inhibitor of the receptor tyrosine kinases(TRK)( TrkA and TrkC with IC50s of 0.6 and <2.5 nM, respectively) | |||
T15790 | Lucifer Yellow CH dilithium salt | ||
Lucifer Yellow CH dilithium salt is a fluorescent dye that can be commonly used for selective staining and the study of photodynamic disruption of eukaryotic and subcellular structures. | |||
T5401 | GSK2983559 active metabolite | GSK2983559,RIPK2 inhibitor 1,RIPK2-IN-1 | RIP kinase |
GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor. | |||
T6719 | Varlitinib | ASLAN001,ARRY-334543 | HER |
Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5213 | Acetyl phosphate(lithium potassium) | Lithium potassium acetyl phosphate,Acetylphosphoric acid | Others , Endogenous Metabolite |
Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. Acetyl phosphate lithium potassiu is generated from sul... | |||
T20793 | Magnesium Lithospermate B | Monomethyl lithospermate B,Lithospermate B | Others |
Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is... | |||
T35792 | Isolithocholic Acid | 3-Epilithocholic acid,3β-Hydroxy-5β-cholanic acid,β-Lithocholic acid,isoLCA | Endogenous Metabolite |
Isolithocholic Acid (3-Epilithocholic acid) (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic Acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate. | |||
T0256 | Citric acid trilithium salt tetrahydrate | Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate | Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR |
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways... | |||
T0589 | Xylitol | Adonitol,Ribitol,Xylite,D-Xylitol,Adonite | Others , Endogenous Metabolite , Autophagy |
Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener. | |||
T4854 | Acetoacetic acid lithium salt | LithoTab acetoacetate,Lithium acetoacetate,Lithium 3-Oxobutyrate | Others , Endogenous Metabolite |
Acetoacetic acid lithium salt (Lithium 3-Oxobutyrate) is a weak organic acid that can be produced in the human liver under certain conditions of poor Metabolism leading to excessive fatty acid breakdown (diabetes mellitu... | |||
T3756 | Allitol | Allodulcit,Allodulcitol,d-allitol | Others |
Allitol (d-allitol) is a substrate for the production of L-form ketoses and aldoses. | |||
TQ0269 | Melittoside | Antioxidant | |
Melittoside is a natural phenolic glycoside found in the nectar of the Melitto genus. It has antioxidant, anti-inflammatory and antifungal activities, as well as research into its potential use in the treatment of variou... | |||
T4727 | Taurolithocholic acid sodium salt | Sodium taurolithocholate | Others , Calcium Channel |
Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors. | |||
TN7030 | Heteroclitin G | Others | |
Heteroclitin G was found as potential biomarkers of KIS blood-replenishing activity, and quantitative analysis provided a research basis for further pharmacological research. | |||
TN1722 | Hamamelitannin | Antifection | |
Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a hig... | |||
TN1855 | Laurolitsine | (+)-Norboldine | Others |
Laurolitsine ((+)-Norboldine), an alkaloid, is extracted from the leaves of Peumus boldus Molina. | |||
T8207 | Evolitrine | Others | |
Evolitrine is an anti-inflammatory substance derived from Acronychia pedunculata. | |||
T13522 | 7-Ketolithocholic acid | 3α-Hydroxy-7-oxo-5β-cholanic acid | Endogenous Metabolite |
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholester... | |||
TN7108 | Urolithin C | Apoptosis , Calcium Channel , Reactive Oxygen Species , IGF-1R , Endogenous Metabolite | |
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway. | |||
TN1028 | Militarine | Others | |
Militarine has plant inhibitory effect against the growth of Italian ryegrass, timothy, and B. striata. | |||
T5738 | 7-Epi 10-desacetyl paclitaxel | 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol | Others |
7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) shows IC50 values of 0.085 nM, against HeLa cells. | |||
T2202 | Lithocholic acid | 3α-Hydroxy-5β-cholanic acid | Apoptosis , Others , FXR , Endogenous Metabolite , Autophagy |
Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is... | |||
T0968 | Paclitaxel | Taxol,NSC 125973 | Apoptosis , Microtubule Associated , Autophagy |
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy. | |||
T16338 | Norgestimate metabolite Norelgestromin | 17-Deacetyl norgestimate,17-Deacylnorgestimate | Drug Metabolite |
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl es... | |||
T30969 | Clitocine | Apoptosis , BCL | |
Clitocine, an adenosine analogue derived from mushrooms, is a potent transcriptional readout agent, an inhibitor of nonsense mutations, and has anticancer activity, inducing the production of p53 protein in cells carryin... | |||
T21165 | Pellitorine | AI3-19560,Pellitorin | TRP/TRPV Channel |
Pellitorine (Pellitorin) is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist. | |||
T3S1916 | Heteroclitin D | Calcium Channel | |
1. Heteroclitin D can inhibit L-type calcium channels. 2. Heteroclitin D might be a valuable antitumor promoter or chemopreventor. | |||
T5749 | 10-Deacetyl-7-xylosyl paclitaxel | 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,10-Deacetylpaclitaxel 7-Xyloside | Others , Microtubule Associated |
10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer. | |||
T8299 | Dimethyl lithospermate B | dmLSB | Sodium Channel |
Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist. | |||
T3784 | Lithospermoside | Griffonin | Others |
Lithospermoside (Griffonin) has anti-oxidant, anti-tumor promoting activities. | |||
TN1020 | Monomelittoside | Danmelittoside | Others |
Monomelittoside (Danmelittoside), a compound extracted from the venom of the Chinese honeybee, is a flavonoid glycoside that has been found to have anti-inflammatory, anti-tumor and anti-diabetic properties. It has also ... | |||
T8878 | Urolithin M6 | 3,8,9,10-tetrahydroxy urolithin | Others |
urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic | |||
TN1513 | Clitorin | PKC , Antifection | |
Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential. | |||
T20604L | Litorin acetate(55749-97-8 Free base) | Bombesin Receptor | |
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the n... | |||
T3683 | lithospermic acid | HIV Protease | |
lithospermic acid is a potent anti-HIV agent and shows anti-gonadotrophic and anti-thyroidal effects. | |||
T1529 | Miglitol | BAY1099,BAY-m1099 | Others |
Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity. | |||
T31964 | Glycolithocholic acid | Lithocholic acid glycine conjugate,Lithocholylglycine | Others |
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid. | |||
T13265 | Urolithin B | ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK | |
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit... | |||
T7174 | Urolithin A | Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite | |
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties. | |||
T38478 | Mevalonic acid 5-pyrophosphate tetralithium | Mevalonicacid5-diphosphatetetralithium,Mevalonic acid 5-pyrophosphate tetralithium,5-Diphosphomevalonic acid tetralithium | |
Mevalonic acid 5-pyrophosphate (also known as 5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite involved in the mevalonate pathway. | |||
T74005 | Urolithin D | ||
Urolithin D acts as a competitive and reversible antagonist for EphA receptors, displaying selectivity within its class [1]. | |||
TN3323 | Monomethyl lithospermate | Lithospermic acid monomethyl ester | Akt , PI3K |
Monomethyl lithospermate (Lithospermic acid monomethyl ester) has potential antiviral activity, alleviating ischemic stroke injury in vivo in middle cerebral artery occlusion mice by activating PI5K/Akt signaling and pro... | |||
T19426 | Mevalonic acid lithium salt | Others | |
Mevalonic acid lithium salt, is essential for cell growth and proliferation. | |||
TMA2563 | Pedalitin | Tyrosinase | |
Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosmarinate and Pedalitin are mixed-type inhibitors. | |||
T78487 | Laurolitsine hydrochloride | (+)-Norboldine hydrochloride | |
Laurolitsine hydrochloride, an alkaloid extracted from Phoebe formosana, exhibits weak anti-inflammatory properties. | |||
T82209 | Heteroclitin A | ||
Heteroclitin A is a lignan obtained from the stems of Schisandra propinqua (Kurcz.) Baill. | |||
TN4208 | Heteroclitin C | Others | |
Heteroclitin C is a natural product from Kadsura heteroclita. | |||
T74293 | Allolithocholic acid | ||
Allolithocholic acid, a steroid acid present in normal serum and feces, aids in the excretion, absorption, and transport of fats and sterols within the intestine and liver [1]. | |||
TN5531 | Eupalitin | 3,5,4'-Trihydroxy-6,7-dimethoxyflavone | |
Eupalitin is a natural product for research related to life sciences. The catalog number is TN5531 and the CAS number is 29536-41-2. | |||
TN3109 | 5-Epilithospermoside | Others | |
(-)-5-Epilithospermoside is proposed as a potential marker of botanical origin for phacelia honey. | |||
TN4742 | Patulitrin | Antifection | |
Patulitrin has antioxidant, anti-inflammatory, and larvicidal activities, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice. | |||
T32800 | Littorine | (R)-(-)-Littorine | |
Littorine is a tropane alkaloid found in a variety of plants including Datura and Atropa belladonna. It is closely related in chemical structure to atropine, hyoscyamine, and scopolamine, which all share a common biosynt... | |||
T73758 | Glycolithocholic acid 3-sulfate | ||
Glycolithocholic acid 3-sulfate (SLCG), a cholic acid derivative and glycolithocholic acid metabolite, effectively inhibits HIV-1 replication in vitro. This compound holds potential for researching HIV infection and gall... | |||
T20604 | Litorin | ||
Litorin, an amphibian bombesin peptide derivative, is found to suppress the nutriment, to stimulate the contraction of smooth muscle, to stimulate gastrin, gastric acid, and pancreatic secretion. | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-04722 | DcR1/TRAILR3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most ... | |||
TMPH-03715 | Y-STB Protein, Yersinia enterocolitica, Recombinant (His & SUMO) | Yersinia enterocolitica | E. coli |
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. Could play an important role in pathogenesis. | |||
TMPH-02364 | Japanese encephalitis virus Genome polyprotein (His & SUMO) | JEV | E. coli |
Japanese encephalitis virus Genome polyprotein (His & SUMO) is expressed in E. coli. | |||
TMPY-04652 | Influenza A H17N10 (A/little yellow-shouldered bat/Guatemala/164/2009) Hemagglutinin/HA Protein (His) | H17N10 | Baculovirus Insect Cells |
Influenza A H17N10 (A/little yellow-shouldered bat/Guatemala/164/2009) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession numb... | |||
TMPH-03720 | YscM Protein, Yersinia enterocolitica, Recombinant (His & SUMO) | Yersinia enterocolitica | E. coli |
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function. | |||
TMPH-02763 | Lithostathine-1/Reg1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Lithostathine-1/Reg1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-02484 | SLITRK4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SLIT and NTRK-like family proteins 4 is a member of the SLIT and NTRK-like family. This protein is characterized as an integral membrane protein that has two leucine-rich repeat (LRR) domains and a carboxy-terminal domai... | |||
TMPY-00922 | SLITRK1 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
SLITRK1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 95 kDa and the accession number is Q96PX8. | |||
TMPH-03719 | YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc) | Yersinia enterocolitica | E. coli |
Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to... | |||
TMPH-03716 | Invasin Protein, Yersinia enterocolitica, Recombinant (His & SUMO) | Yersinia enterocolitica | E. coli |
Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins. | |||
TMPH-03718 | YopB Protein, Yersinia enterocolitica, Recombinant (His) | Yersinia enterocolitica | E. coli |
Plays a role in virulence. | |||
TMPY-03058 | SLITL2/VASN Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular... | |||
TMPY-00923 | SLITRK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SLITRK1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 105-115 kDa and the accession number is Q96PX8. | |||
TMPY-04234 | Influenza A H17N10 (A/little yellow-shouldered bat/Guatemala/164/2009) Hemagglutinin/HA1 Protein (His) | H17N10 | HEK293 Cells |
Influenza A H17N10 (A/little yellow-shouldered bat/Guatemala/164/2009) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession num... | |||
TMPY-03063 | SLITRK6 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SLITRK6 belongs to the SLITRK family. Members of this family share two conserved leucine-rich repeat domains in the extracellular domain. SLITRK6 contains 11 LRR (leucine-rich) repeats, 2 LRRCT domains and 2 LRRNT domain... | |||
TMPH-03717 | YopE Protein, Yersinia enterocolitica, Recombinant (His) | Yersinia enterocolitica | E. coli |
Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis. |
Cat No. | Product Name | ||
---|---|---|---|
L7810 | High Solubility Polyfunctional Group Fragment Library | 1159 compounds | |
Highly soluble multifunctional fragment library contains 1159 kinds of fragment molecules. | |||
L6001 | Mini Fungal Metabolite Natural Product Screening Library | Inquiry | |
L7820 | High Solubility Micro Fragment Library | 1081 compounds | |
The compound library of highly soluble micro-fragments consists of 1081 low-molecular-weight fragments. | |||
L7840 | High Solubility FragLite Fragment Library | 796 compounds | |
The highly soluble halogenated fragment library contains 796 halogenated fragment compounds. | |||
L7830 | High Solubility Pharmacophore Fragment Library | 985 compounds | |
High Solubility Pharmacophore Fragment library contains 985 fragment small molecules. | |||
L2540 | Gut Microbial Metabolite Library | 607 compounds | |
A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS; | |||
L2530 | Mouse Metabolite Compound Library | 218 compounds | |
A unique collection of 218 mouse metabolites, which can be used for HTS and HCS; | |||
L7850 | High Solubility 3D Diversity Fragment Library | 1079 compounds | |
The library of highly soluble 3D structural diversity fragments contains 1079 compounds. | |||
L2570 | Human Metabolite Library | 4454 compounds | |
A unique collection of 4454 human metabolites for high-throughput, high-content screening. | |||
L5800 | Drug Metabolite/Impurity Library | 197 compounds | |
A unique collection of 197 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS); | |||
L7800 | High Solubility Fragment Library | 2728 compounds | |
Structurally diverse, medicinally active, and unique chemistry (strong IP potential); | |||
L2501 | Human Endogenous Metabolite Compound Library Plus | 1283 compounds | |
A unique collection of 1283 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening. | |||
L2500 | Human Endogenous Metabolite Library | 499 compounds | |
A collection of 499 selected human endogenous metabolites for high throughput and high content screening. | |||
L6200 | The Yao nationality medicine Library | 221 compounds | |
A collection of 221 natural product molecules originated from Yao medicine, which can be used for high-throughput and high-content screening. | |||
L7870 | Carboxylic Acid Fragment Library With Solubility | 1806 compounds | |