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Globotriaosylceramide (non-hydroxy) (porcine RBC) is a glycosphingolipid found in the cell membranes of mammals. It is a central pathogenic molecule in Fabry disease, with its levels modifiable by supplementing α-galactosidase A. This compound enhances B cell receptor signaling by regulating the localization of the coreceptor CD19 and can serve as a vaccine adjuvant, promoting a broad and cross-protective antibody response. Additionally, Globotriaosylceramide (non-hydroxy) (porcine RBC) aids in wound healing and decreases scar formation by modulating fibroblast heterogeneity.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Globotriaosylceramide (non-hydroxy) (porcine RBC) is a glycosphingolipid found in the cell membranes of mammals. It is a central pathogenic molecule in Fabry disease, with its levels modifiable by supplementing α-galactosidase A. This compound enhances B cell receptor signaling by regulating the localization of the coreceptor CD19 and can serve as a vaccine adjuvant, promoting a broad and cross-protective antibody response. Additionally, Globotriaosylceramide (non-hydroxy) (porcine RBC) aids in wound healing and decreases scar formation by modulating fibroblast heterogeneity. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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