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β-Anomer

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Catalog No. TNU0422Cas No. 356782-84-8

β-Anomer shows antiviral properties.

β-Anomer

β-Anomer

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Purity: 99.93%
Catalog No. TNU0422Cas No. 356782-84-8
β-Anomer shows antiviral properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$46In StockIn Stock
50 mg$68In StockIn Stock
100 mg$103-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.93%
Appearance:Solid
Color:White
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Product Introduction

β-Anomer AI Summary
β-Anomer exhibits significant antiviral activity against Yellow Fever Virus (YFV) and Influenza viruses A and B. In Syrian golden hamsters infected with YFV, the compound effectively reduces serum alanine aminotransferase levels, delays mortality, and decreases viral titers in the liver, particularly when administered at higher dosages. However, it shows limited efficacy in inhibiting cytopathic effects in African green monkey Vero cells infected with YFV, with EC50 values ranging from 1,080,000 nM to 2,630,000 nM, and has a Selectivity Index above 3.6. Against Influenza virus strains in MDCK cells, β-Anomer significantly reduces viral replication, demonstrating higher potency against the Influenza B strain with EC50 values between 19,000 nM and 24,000 nM. The compound's cytotoxic effects are low, with CC50 values exceeding 250,000 nM. β-Anomer does not exhibit antifungal or antibacterial activity against a variety of pathogens, including Candida albicans, Cryptococcus neoformans, and several bacterial strains such as Escherichia coli and Staphylococcus aureus. It also does not cause hemolysis of human red blood cells, and it shows low cytotoxicity against HEK293 cells. Overall, β-Anomer shows promise as an antiviral agent, particularly in animal models, but further studies are needed to fully understand its efficacy and safety profiles..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
β-Anomer shows antiviral properties.
Chemical Properties
Molecular Weight271.23
FormulaC10H13N3O6
Cas No.356782-84-8
SmilesO[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)C(C(N)=O)=NC=C2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (184.35 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6869 mL18.4345 mL36.8691 mL184.3454 mL
5 mM0.7374 mL3.6869 mL7.3738 mL36.8691 mL
10 mM0.3687 mL1.8435 mL3.6869 mL18.4345 mL
20 mM0.1843 mL0.9217 mL1.8435 mL9.2173 mL
50 mM0.0737 mL0.3687 mL0.7374 mL3.6869 mL
100 mM0.0369 mL0.1843 mL0.3687 mL1.8435 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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