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N-Arachidonylglycine-d8

Name: N-Arachidonylglycine-d8
Brand: TargetMol
SKU: TMID-0504
Rating: 4.5 (1 reviews)

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Catalog No. TMID-0504Cas No. 1159908-44-7

N-Arachidonylglycine-d8 is the deuterium-labeled version of N-Arachidonylglycine. N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endogenous cannabinoid anandamide (AEA), functions as a GPR18 agonist with an EC50 of 44.5 nM. Unlike AEA, it does not show activity at CB1 and CB2 receptors. It inhibits GLYT2 with an IC50 of 5.1 μM and is an effective stimulator of endometrial cell migration.

N-Arachidonylglycine-d8

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Catalog No. TMID-0504Cas No. 1159908-44-7

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

In vivo

Administering N-Arachidonylglycine at 10 mg/kg orally leads to a 9-fold increase in blood anandamide levels. A single oral dose of N-Arachidonylglycine at 1.2 mg/kg results in a notable 70% decrease in peritoneal cell numbers.

Chemical Properties

Molecular Weight	369.57
Formula	C₂₂H₃₅NO₃
Cas No.	1159908-44-7
Smiles	C(CCC(NCC(O)=O)=O)/C(=C(\C/C(=C(\C/C(=C(\C/C(=C(\CCCCC)/[2H])/[2H])/[2H])/[2H])/[2H])/[2H])/[2H])/[2H]

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc