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Salicin

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Catalog No. T0443Cas No. 138-52-3
Alias Salicoside, Salicine, D-(−)-Salicin

Salicin (Salicine), a phenol β-glycoside produced from willow bark, shows anti-inflammatory functions.

Salicin

Salicin

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Purity: 99.86%
Catalog No. T0443Alias Salicoside, Salicine, D-(−)-SalicinCas No. 138-52-3
Salicin (Salicine), a phenol β-glycoside produced from willow bark, shows anti-inflammatory functions.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 g$39-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.86%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Salicin (Salicine), a phenol β-glycoside produced from willow bark, shows anti-inflammatory functions.
In vivo
Salicin is a prodrug that is gradually transported to the lower intestine where it is metabolized by intestinal bacteria into saligenin, which is then absorbed by the body and further converted into salicylic acid. Thus, it can exert antipyretic effects without causing gastric damage.
SynonymsSalicoside, Salicine, D-(−)-Salicin
Chemical Properties
Molecular Weight286.28
FormulaC13H18O7
Cas No.138-52-3
SmilesO([C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C2=C(CO)C=CC=C2
Relative Density.1.504g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 250 mg/mL (873.27 mM), Sonication is recommended.
H2O: 19.2 mg/mL (67.07 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.4931 mL17.4654 mL34.9308 mL174.6542 mL
5 mM0.6986 mL3.4931 mL6.9862 mL34.9308 mL
10 mM0.3493 mL1.7465 mL3.4931 mL17.4654 mL
20 mM0.1747 mL0.8733 mL1.7465 mL8.7327 mL
50 mM0.0699 mL0.3493 mL0.6986 mL3.4931 mL
DMSO
1mg5mg10mg50mg
100 mM0.0349 mL0.1747 mL0.3493 mL1.7465 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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