store under nitrogen,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist with anticancer, antitumor, anti-inflammatory, and neuroprotective activities, induces apoptosis, regulates the cell cycle, and can be used to study advanced tumors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 258.00 | |
5 mg | 5 days | $ 435.00 |
Description | 9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist with anticancer, antitumor, anti-inflammatory, and neuroprotective activities, induces apoptosis, regulates the cell cycle, and can be used to study advanced tumors. |
In vitro | In CA 9-22 and NA cells, 9-cis-Retinoic acid (1 μM, 10 μM; 0 day, 1 day, 3 days, 5 days) significantly decreased proliferation[1]. |
In vivo | In male C57BL/6J mice (6-8 weeks old; 19-22 g), following bile duct ligation, treatment with 9-cis-Retinoic Acid (1 mg/kg; intravenous injection; once daily; for 10 days) significantly decreased serum ALT and AST levels and alleviated hepatic necrosis[3]. |
Synonyms | Alitretinoin |
Molecular Weight | 300.44 |
Formula | C20H28O2 |
CAS No. | 5300-03-8 |
store under nitrogen,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15 mg/mL (49.93 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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9-cis-Retinoic Acid 5300-03-8 Apoptosis 9cisRetinoic Acid 9 cis Retinoic Acid Alitretinoin inhibitor inhibit