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Oleoylcarnitine

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Catalog No. T12295Cas No. 38677-66-6
Alias Oleoyl-L-carnitine

Oleoylcarnitine (Oleoyl-L-carnitine) inhibits adenine nucleotide translocase (AdNT) activity with an ic50 of 14 μM.Oleoylcarnitine is an important indicator of neurodegeneration.

Oleoylcarnitine

Oleoylcarnitine

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Purity: 99.91%
Catalog No. T12295Alias Oleoyl-L-carnitineCas No. 38677-66-6
Oleoylcarnitine (Oleoyl-L-carnitine) inhibits adenine nucleotide translocase (AdNT) activity with an ic50 of 14 μM.Oleoylcarnitine is an important indicator of neurodegeneration.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$52In StockIn Stock
5 mg$135In StockIn Stock
10 mg$196In StockIn Stock
25 mg$336-In Stock
50 mgInquiry-In Stock
100 mgInquiry-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.91%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Oleoylcarnitine (Oleoyl-L-carnitine) inhibits adenine nucleotide translocase (AdNT) activity with an ic50 of 14 μM.Oleoylcarnitine is an important indicator of neurodegeneration.
In vitro
In Dih 10 cells and HCC cells, Oleoylcarnitine (5, 25, 50 µM; 24, 48 hours) enhanced the self-renewal of HCC cells through STAT3 activation, contributing directly to hepatocarcinogenesis[1].
SynonymsOleoyl-L-carnitine
Chemical Properties
Molecular Weight425.65
FormulaC25H47NO4
Cas No.38677-66-6
Smiles[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)(C[N+](C)(C)C)CC([O-])=O
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (58.73 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3493 mL11.7467 mL23.4935 mL117.4674 mL
5 mM0.4699 mL2.3493 mL4.6987 mL23.4935 mL
10 mM0.2349 mL1.1747 mL2.3493 mL11.7467 mL
20 mM0.1175 mL0.5873 mL1.1747 mL5.8734 mL
50 mM0.0470 mL0.2349 mL0.4699 mL2.3493 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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