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Omega-3 acid ethyl esters

(Synonyms: P-OM3) Copy Product Info
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Synonyms: P-OM3

Catalog No. TYD-10184 Copy Product Info
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Omega-3 acid ethyl esters (P-OM3) is a type of ω-3 polyunsaturated fatty acid. It is utilized in research focused on severe hypertriglyceridemia and cardiovascular diseases.

Omega-3 acid ethyl esters

Cas No. 861006-80-6
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For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Omega-3 acid ethyl esters (P-OM3) is a type of ω-3 polyunsaturated fatty acid. It is utilized in research focused on severe hypertriglyceridemia and cardiovascular diseases.
In vitro
Omega-3 acid ethyl esters reduce triglyceride synthesis, enhance peroxisomal β-oxidation, and upregulate fatty acid metabolism. They inhibit fatty acid esterification and release, increase lipoprotein lipase activity, promote triglyceride clearance, decrease hepatic very-low-density lipoprotein cholesterol production, alter low-density lipoprotein cholesterol particle structure, inhibit platelet aggregation, and lower blood pressure and heart rate. Additionally, they reduce the risk of ventricular fibrillation or tachycardia, lower levels of vitamin K-dependent clotting factors, and decrease platelet arachidonic acid and thromboxane A2 levels, potentially prolonging bleeding time.
SynonymsP-OM3
Chemical Properties
Molecular Weight687.05
FormulaC46H70O4
Cas No.861006-80-6
SmilesC(=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)\CCC(OCC)=O.C(=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)\CCCC(OCC)=O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
µL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Omega-3 acid ethyl esters in vitro | Omega-3 acid ethyl esters formula | Omega-3 acid ethyl esters molecular weight