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N,N'-Dimethylarginine-d6

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Catalog No. TMIH-0361Cas No. 1331888-08-4
Alias Symmetric dimethylarginine-d6, SDMA-d6

N,N'-Dimethylarginine-d6 (SDMA-d6) is a 2H-labeled N,N'-Dimethylarginine, a 202-Da methylated analog of the amino acid arginine, formed during post-translational methylation by methyltransferases.

N,N'-Dimethylarginine-d6

N,N'-Dimethylarginine-d6

😃Good
Catalog No. TMIH-0361Alias Symmetric dimethylarginine-d6, SDMA-d6Cas No. 1331888-08-4
N,N'-Dimethylarginine-d6 (SDMA-d6) is a 2H-labeled N,N'-Dimethylarginine, a 202-Da methylated analog of the amino acid arginine, formed during post-translational methylation by methyltransferases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$1987-10 days7-10 days
5 mg$7457-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Description
N,N'-Dimethylarginine-d6 (SDMA-d6) is a 2H-labeled N,N'-Dimethylarginine, a 202-Da methylated analog of the amino acid arginine, formed during post-translational methylation by methyltransferases.
SynonymsSymmetric dimethylarginine-d6, SDMA-d6
Chemical Properties
Molecular Weight208.29
FormulaC8H12D6N4O2
Cas No.1331888-08-4
SmilesC(=NCCC[C@@H](C(O)=O)N)(NC([2H])([2H])[2H])NC([2H])([2H])[2H]
ColorYellow
AppearanceLiquid
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 40 mg/mL (192.04 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM4.8010 mL24.0050 mL48.0100 mL240.0499 mL
5 mM0.9602 mL4.8010 mL9.6020 mL48.0100 mL
10 mM0.4801 mL2.4005 mL4.8010 mL24.0050 mL
20 mM0.2400 mL1.2002 mL2.4005 mL12.0025 mL
50 mM0.0960 mL0.4801 mL0.9602 mL4.8010 mL
100 mM0.0480 mL0.2400 mL0.4801 mL2.4005 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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