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1,4-Diaminobutane Dihydrochloride

🥰Excellent
Catalog No. T22213Cas No. 333-93-7
Alias 1,4-butanediamine Dihydrochloride

1,4-Diaminobutane Dihydrochloride (1,4-butanediamine Dihydrochloride) has antidepressant and analgesic effects. It regulates plant defense against environmental stresses by directly killing fungi and inducing resistance mechanisms, enhancing post-harvest mango fruit resistance to Colletotrichum gloeosporioides.

1,4-Diaminobutane Dihydrochloride
Other Forms of 1,4-Diaminobutane Dihydrochloride:
1,4-ButanediamineT4865110-60-1
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1,4-Diaminobutane Dihydrochloride

🥰Excellent
Purity: 99.88%
Catalog No. T22213Alias 1,4-butanediamine DihydrochlorideCas No. 333-93-7
1,4-Diaminobutane Dihydrochloride (1,4-butanediamine Dihydrochloride) has antidepressant and analgesic effects. It regulates plant defense against environmental stresses by directly killing fungi and inducing resistance mechanisms, enhancing post-harvest mango fruit resistance to Colletotrichum gloeosporioides.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$30In StockIn Stock
500 mg$62In StockIn Stock
1 g$89In StockIn Stock
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.88%
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Product Introduction

Bioactivity
Description
1,4-Diaminobutane Dihydrochloride (1,4-butanediamine Dihydrochloride) has antidepressant and analgesic effects. It regulates plant defense against environmental stresses by directly killing fungi and inducing resistance mechanisms, enhancing post-harvest mango fruit resistance to Colletotrichum gloeosporioides.
In vitro
1,4-Diaminobutane Dihydrochloride (100-1000 μM, 24 h) stimulated the growth of CT-26 tumor cells. [1]
1,4-Diaminobutane Dihydrochloride (33.2 mmol/L, 24h) disrupted epithelial compact junction (TJ) integrity in isolated mouse colon tissue. [2]
1,4-Diaminobutane Dihydrochloride (0.25-1 mmol/L) significantly reduced bacterial growth in a concentration-dependent manner.
In vivo
Administration of 1, 4-diaminobutane Dihydrochloride in mice exacerbated colon inflammation and increased intestinal permeability. [2]
1,4-Diaminobutane Dihydrochloride (1% concentration added to drinking water) reduces EcNC101 colonization and tumor development in AOM/DSS mouse models of colorectal cancer. [3]
Synonyms1,4-butanediamine Dihydrochloride
Chemical Properties
Molecular Weight161.07
FormulaC4H14Cl2N2
Cas No.333-93-7
SmilesNCCCCN.Cl.Cl
Relative Density.1.2524 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5 mg/mL (31.04 mM), Sonication is recommended.
H2O: 40 mg/mL (248.34 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (6.21 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM6.2085 mL31.0424 mL62.0848 mL310.4240 mL
5 mM1.2417 mL6.2085 mL12.4170 mL62.0848 mL
10 mM0.6208 mL3.1042 mL6.2085 mL31.0424 mL
20 mM0.3104 mL1.5521 mL3.1042 mL15.5212 mL
H2O
1mg5mg10mg50mg
50 mM0.1242 mL0.6208 mL1.2417 mL6.2085 mL
100 mM0.0621 mL0.3104 mL0.6208 mL3.1042 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Keywords

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