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2'-O-Methylinosine

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Catalog No. TNU0003Cas No. 3881-21-8
Alias 2'-(o-Methyl)-inosine

2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally active purine nucleoside analog with antihypertensive activity.

2'-O-Methylinosine

2'-O-Methylinosine

😃Good
Purity: 99.88%
Catalog No. TNU0003Alias 2'-(o-Methyl)-inosineCas No. 3881-21-8
2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally active purine nucleoside analog with antihypertensive activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30-In Stock
50 mgPreferential-In Stock
1 mL x 10 mM (in DMSO)$39-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.88%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally active purine nucleoside analog with antihypertensive activity.
In vitro
2'-O-Methylinosine effectively inhibits FrC6 virus reverse transcriptase activity in cell-free systems. [1]
In vivo
2'-O-Methylinosine (100 mg/kg, ip) has a significant antihypertensive effect in rats. [2]
Synonyms2'-(o-Methyl)-inosine
Chemical Properties
Molecular Weight282.25
FormulaC11H14N4O5
Cas No.3881-21-8
SmilesO(C)[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=CN3)O[C@H](CO)[C@H]1O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (283.44 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5430 mL17.7148 mL35.4296 mL177.1479 mL
5 mM0.7086 mL3.5430 mL7.0859 mL35.4296 mL
10 mM0.3543 mL1.7715 mL3.5430 mL17.7148 mL
20 mM0.1771 mL0.8857 mL1.7715 mL8.8574 mL
50 mM0.0709 mL0.3543 mL0.7086 mL3.5430 mL
100 mM0.0354 mL0.1771 mL0.3543 mL1.7715 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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