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10 FTHF disodium (Synonyms: 10FTHF disodium, 10-Formyltetrahydrofolic acid disodium, 10-Formyltetrahydrofolate...)

Name: 10 FTHF disodium
Brand: TargetMol
SKU: T73731
Rating: 4.5 (1 reviews)

Catalog No. T73731 Copy Product Info

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10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate, a formyl donor in anabolism, involved in the synthesis of purine compounds.

10 FTHF disodium

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Catalog No. T73731

Synonyms 10FTHF disodium, 10-Formyltetrahydrofolic acid disodium, 10-Formyltetrahydrofolate disodium

10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate, a formyl donor in anabolism, involved in the synthesis of purine compounds.

Cas No. 914800-65-0

Pack Size	Price	USA Stock	Global Stock	Quantity
1 mg	Inquiry	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate, a formyl donor in anabolism, involved in the synthesis of purine compounds.
In vivo	In male Sprague-Dawley rats, a significant increase in the level of 10 FTHF disodium in the liver was observed after 30 and 60 minutes of administration of 1.3 mmol/kg methionine. [1]
Synonyms	10FTHF disodium, 10-Formyltetrahydrofolic acid disodium, 10-Formyltetrahydrofolate disodium

Chemical Properties

Molecular Weight	517.4
Formula	C₂₀H₂₁N₇Na₂O₇
Cas No.	914800-65-0
Smiles	Nc1nc(=O)c2c([nH]1)NCC(CN(C=O)c1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1)N2.[Na+].[Na+]

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 1 mg/mL (1.93 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9327 mL	9.6637 mL	19.3274 mL	96.6370 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc