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Acetoacetic acid
🥰Excellent
Catalog No. T73734Cas No. 541-50-4
Alias 3-oxobutanoic acid
Acetoacetic acid (3-oxobutanoic acid) is a β-keto acid and oxidative stress inducer, produced in the body when poor hepatic metabolism leads to excessive catabolism of fatty acids, is involved in the process of gluconeogenesis, and can be used as an indicator of in ketoacidosis.
Acetoacetic acid
🥰Excellent
Purity: 99.85%
Catalog No. T73734Alias 3-oxobutanoic acidCas No. 541-50-4
Acetoacetic acid (3-oxobutanoic acid) is a β-keto acid and oxidative stress inducer, produced in the body when poor hepatic metabolism leads to excessive catabolism of fatty acids, is involved in the process of gluconeogenesis, and can be used as an indicator of in ketoacidosis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $60 | - | In Stock | |
| 5 mg | $132 | In Stock | In Stock | |
| 10 mg | $198 | - | In Stock | |
| 25 mg | $337 | - | In Stock | |
| 50 mg | $490 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.85%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Acetoacetic acid (3-oxobutanoic acid) is a β-keto acid and oxidative stress inducer, produced in the body when poor hepatic metabolism leads to excessive catabolism of fatty acids, is involved in the process of gluconeogenesis, and can be used as an indicator of in ketoacidosis. |
| In vitro | Methods: Acetoacetic acid (0.6, 2.4, 4.8 mM, 24 h) was used to treat dairy cow hepatocytes, and the related enzyme activities and protein expressions were determined. Results: Acetoacetic acid can reduce the mRNA expression and enzyme activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) in a dose-dependent manner, increase the malondialdehyde (MDA) content, induce oxidative stress, and downregulate the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low-density lipoprotein receptor (LDLR), inhibit the assembly of very low-density lipoprotein (VLDL), and lead to the accumulation of intracellular triglycerides (TG) and the reduction of VLDL content in the culture medium. [1] |
| Synonyms | 3-oxobutanoic acid |
| Molecular Weight | 102.09 |
| Formula | C4H6O3 |
| Cas No. | 541-50-4 |
| Smiles | O=C(O)CC(=O)C |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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