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L-Lysine acetate

Name: L-Lysine acetate
Brand: TargetMol
SKU: T2A2498L2
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Purity: 99.97%

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L-Lysine acetate is an essential amino acid for humans. Owing to its unique biological properties, it can be used in mechanistic investigations and research related to vascular calcification (VC) and acute pancreatitis.

Cas No. 57282-49-2

Pack Size	Price	USA Stock	Global Stock	Quantity
10 g	$29	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.97%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	L-Lysine acetate is an essential amino acid for humans. Owing to its unique biological properties, it can be used in mechanistic investigations and research related to vascular calcification (VC) and acute pancreatitis.
In vitro	Methods: Vascular smooth muscle cells (VSMCs) were used as the research object and treated with L-Lysine acetate. Results: L-Lysine acetate decreased plasma iPTH levels and increased plasma concentrations of alanine, proline, arginine and homoarginine, thereby inhibiting apoptosis and mineral deposition in VSMCs. Methods: A systematic analysis was performed on the biological functions and pathological significance of the AKT signaling pathway. Results: AKT mediates cell survival and proliferation by inhibiting pro-apoptotic pathways. Dysregulation of the AKT signaling cascade is observed in various cancers and is associated with tumor invasiveness. Abnormal AKT function enhances cell proliferation, growth and survival, and induces apoptosis resistance. AKT1-related inhibitors can facilitate cancer-related research [1].
In vivo	Methods: Adenine-induced rats were orally administered L-Lysine acetate (40 μg/kg; p.o.) by gavage. Results: L-Lysine acetate ameliorated arterial calcification in adenine-treated rats and protected their femurs against osteoporotic lesions [1]. Methods: Male mice were given L-Lysine acetate (10, 400 mg/kg; i.g., p.o.) by gavage and oral administration, respectively. Results: L-Lysine acetate inhibited pancreatic tissue damage [2].

Chemical Properties

Molecular Weight	206.24
Formula	C₈H₁₈N₂O₄
Cas No.	57282-49-2
Smiles	[C@H](CCCCN)(C(O)=O)N.C(C)(O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 93.34 mg/mL (452.58 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	4.8487 mL	24.2436 mL	48.4872 mL	242.4360 mL
5 mM	0.9697 mL	4.8487 mL	9.6974 mL	48.4872 mL
10 mM	0.4849 mL	2.4244 mL	4.8487 mL	24.2436 mL
20 mM	0.2424 mL	1.2122 mL	2.4244 mL	12.1218 mL
50 mM	0.0970 mL	0.4849 mL	0.9697 mL	4.8487 mL
100 mM	0.0485 mL	0.2424 mL	0.4849 mL	2.4244 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Keywords

Lysine acetateLysine Acetate

Related Tags: L-Lysine acetate chemical structure | L-Lysine acetate in vivo | L-Lysine acetate in vitro | L-Lysine acetate formula | L-Lysine acetate molecular weight