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Isochenodeoxycholic acid

Name: Isochenodeoxycholic acid
Brand: TargetMol
SKU: T207107
Rating: 4.5 (1 reviews)

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Catalog No. T207107Cas No. 566-24-5

Alias isoCDCA

Isochenodeoxycholic acid (isoCDCA), a bile acid and primary metabolite of ursodeoxycholic acid (UDCA), Isochenodeoxycholic acid exerts protective effects against ethanol-induced damage in HepG2 hepatocytes.

Isochenodeoxycholic acid

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Purity: 99.77%

Catalog No. T207107Alias isoCDCACas No. 566-24-5

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Batch Information

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Purity:99.77%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Isochenodeoxycholic acid (isoCDCA), a bile acid and primary metabolite of ursodeoxycholic acid (UDCA), Isochenodeoxycholic acid exerts protective effects against ethanol-induced damage in HepG2 hepatocytes.
Synonyms	isoCDCA

Chemical Properties

Molecular Weight	392.57
Formula	C₂₄H₄₀O₄
Cas No.	566-24-5
Smiles	C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@H]3O)(C[C@@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 6.30 mg/mL (16.05 mM), Sonication is recommended.

DMSO: 80.00 mg/mL (203.79 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5473 mL	12.7366 mL	25.4732 mL	127.3658 mL
5 mM	0.5095 mL	2.5473 mL	5.0946 mL	25.4732 mL
10 mM	0.2547 mL	1.2737 mL	2.5473 mL	12.7366 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1274 mL	0.6368 mL	1.2737 mL	6.3683 mL
50 mM	0.0509 mL	0.2547 mL	0.5095 mL	2.5473 mL
100 mM	0.0255 mL	0.1274 mL	0.2547 mL	1.2737 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc