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CJ28
(Synonyms: CJ-28, CJ 28) Copy Product Info
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Synonyms: CJ-28, CJ 28
Catalog No. TN11148 Copy Product Info
Purity: 99.34%
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CJ28 is a cortisol biosynthesis inhibitor. In human adrenocortical carcinoma cell models, it significantly reduces cortisol production under both basal and stimulated conditions. The mechanism of action of CJ28 is primarily associated with the inhibition of the steroidogenesis pathway and de novo cholesterol biosynthesis, thereby reducing the supply of cortisol precursors and downregulating hormone synthesis levels.
Cas No. 3047118-54-4
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $42 | - | In Stock | |
| 5 mg | $98 | - | In Stock | |
| 10 mg | $157 | - | In Stock | |
| 25 mg | $289 | - | In Stock | |
| 50 mg | $463 | - | In Stock | |
| 100 mg | $742 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.34%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | CJ28 is a cortisol biosynthesis inhibitor. In human adrenocortical carcinoma cell models, it significantly reduces cortisol production under both basal and stimulated conditions. The mechanism of action of CJ28 is primarily associated with the inhibition of the steroidogenesis pathway and de novo cholesterol biosynthesis, thereby reducing the supply of cortisol precursors and downregulating hormone synthesis levels. |
| Synonyms | CJ-28, CJ 28 |
| Molecular Weight | 331.17 |
| Formula | C14H11BrN4O |
| Cas No. | 3047118-54-4 |
| Smiles | O=C(NC1=CC(Br)=CC=C1)NC2=NC3=CC=CC=C3N2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Related Tags: CJ28 chemical structure | CJ28 formula | CJ28 molecular weight
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