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Mevalonic acid lithium salt

Name: Mevalonic acid lithium salt
Brand: TargetMol
SKU: T19426
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19426Cas No. 2618458-93-6

Alias MVA lithium salt

Mevalonic acid lithium salt (MVA lithium salt) is a precursor of the mevalonic acid pathway, an initiator of cell growth, a key substance in cholesterol synthesis, and stimulates DNA synthesis, morphology transformation, and cell cycling in human lymphocytes from peripheral blood.

Mevalonic acid lithium salt

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Purity: 98%

Catalog No. T19426Alias MVA lithium saltCas No. 2618458-93-6

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$64	-	In Stock
1 mL x 10 mM (in DMSO)	$169	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:98%

Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	Mevalonic acid lithium salt (MVA lithium salt) is a precursor of the mevalonic acid pathway, an initiator of cell growth, a key substance in cholesterol synthesis, and stimulates DNA synthesis, morphology transformation, and cell cycling in human lymphocytes from peripheral blood.
In vitro	Mevalonic acid lithium salt (80, 90, 100, 110 µM) treatment of C2C12 myotubular cells for 72 hours resisted simvastatin-induced reduction in cell viability. [1]
Synonyms	MVA lithium salt

Chemical Properties

Molecular Weight	154.09
Formula	C₆H₁₁LiO₄
Cas No.	2618458-93-6
Smiles	O=C(CC(C)(CCO)O)[O-].[Li+]
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (259.59 mM), Sonication is recommended.

H2O: 80 mg/mL (519.18 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.98 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	6.4897 mL	32.4486 mL	64.8971 mL	324.4857 mL
5 mM	1.2979 mL	6.4897 mL	12.9794 mL	64.8971 mL
10 mM	0.6490 mL	3.2449 mL	6.4897 mL	32.4486 mL
20 mM	0.3245 mL	1.6224 mL	3.2449 mL	16.2243 mL
50 mM	0.1298 mL	0.6490 mL	1.2979 mL	6.4897 mL
100 mM	0.0649 mL	0.3245 mL	0.6490 mL	3.2449 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc