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3-Oxocholic acid

Name: 3-Oxocholic acid
Brand: TargetMol
SKU: T19124
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19124Cas No. 2304-89-4

Alias 3-Ketocholic acid

3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-Oxocholic acid is a steroid acid mainly found in the bile of mammals.

3-Oxocholic acid

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Purity: 99.63%

Catalog No. T19124Alias 3-Ketocholic acidCas No. 2304-89-4

Pack Size	Price	Availability
1 mg	$39	In Stock
5 mg	$89	In Stock
10 mg	$135	In Stock
25 mg	$226	In Stock
50 mg	$336	In Stock
100 mg	$490	In Stock
200 mg	$713	In Stock
1 mL x 10 mM (in DMSO)	$98	In Stock

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Batch Information

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Purity:99.63%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-Oxocholic acid is a steroid acid mainly found in the bile of mammals.
In vivo	Male Goto-Kakizaki (GK) rats underwent Ileal Transposition (IT) surgery, resulting in increased levels of 3-Oxocholic acid in IT rats compared to Sham-IT rats, as revealed by metabolomics analysis [1].
Synonyms	3-Ketocholic acid

Chemical Properties

Molecular Weight	406.56
Formula	C₂₄H₃₈O₅
Cas No.	2304-89-4
Smiles	[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])CC(=O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(O)=O
Relative Density.	1.180 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (221.37 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4597 mL	12.2983 mL	24.5966 mL	122.9831 mL
5 mM	0.4919 mL	2.4597 mL	4.9193 mL	24.5966 mL
10 mM	0.2460 mL	1.2298 mL	2.4597 mL	12.2983 mL
20 mM	0.1230 mL	0.6149 mL	1.2298 mL	6.1492 mL
50 mM	0.0492 mL	0.2460 mL	0.4919 mL	2.4597 mL
100 mM	0.0246 mL	0.1230 mL	0.2460 mL	1.2298 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc