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ADR-925, an active chelated iron metabolite of dexrazoxane, has the ability to protect neonatal rat cardiomyocytes from doxorubicin-induced injury.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $1,120 | In Stock | |
| 5 mg | $2,250 | In Stock | |
| 10 mg | $2,970 | In Stock | |
| 25 mg | $4,490 | In Stock | |
| 50 mg | $5,970 | In Stock |
| Description | ADR-925, an active chelated iron metabolite of dexrazoxane, has the ability to protect neonatal rat cardiomyocytes from doxorubicin-induced injury. |
| In vivo | METHODS: ADR-925 (ICRF 198) (88 mg/kg, intraperitoneal injection, 30 minutes before doxorubicin injection, once a week, 12 times) was administered to mice to observe the protective effect of ADR-925 against the lethal effects of mice. RESULTS In animals pretreated with ADR559, there was partial protection against the lethal effects of doxorubicin. [2] |
| Synonyms | ICRF-198, ICRF198, ICRF 198, ADR925, ADR 925 |
| Molecular Weight | 304.3 |
| Formula | C11H20N4O6 |
| Cas No. | 75459-34-6 |
| Smiles | N([C@H](CN(CC(N)=O)CC(O)=O)C)(CC(N)=O)CC(O)=O |
| Relative Density. | 1.409 g/cm3 (Predicted) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |

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