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4-Octyl itaconate-Bn-S-NH2 (Compound 8b) functions as a vasorelaxant. It releases H₂S slowly and steadily, helping to reduce oxidative stress through antioxidant reactions that depend on Nrf2 activation. It also inhibits the generation of intracellular ROS and cytotoxicity caused by H₂O₂ damage and activates the potassium channel. This compound is applicable in hypertension research.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | 4-Octyl itaconate-Bn-S-NH2 (Compound 8b) functions as a vasorelaxant. It releases H₂S slowly and steadily, helping to reduce oxidative stress through antioxidant reactions that depend on Nrf2 activation. It also inhibits the generation of intracellular ROS and cytotoxicity caused by H₂O₂ damage and activates the potassium channel. This compound is applicable in hypertension research. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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