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Choline

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Catalog No. TRF-00004 Copy Product Info
Purity: 99.90%
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Choline is the parent compound of choline compounds, with a structure in which the amino group of ethanolamine is substituted by three methyl groups. Choline acts as a neurotransmitter, nutrient, and allergen, and is an endogenous metabolite in mice, Saccharomyces cerevisiae, plants, Escherichia coli, humans, and Daphnia magna. Choline is involved in the regulation of gallbladder function, hepatic physiology, and the synthesis of the key lipid lecithin; it promotes fat and cholesterol metabolism, reduces excessive fat accumulation in the liver, and can also be used to alleviate symptoms associated with Parkinsonism and tardive dyskinesia. Choline deficiency may cause abnormal hepatic fat deposition, hypertension, gastric ulcers, liver and kidney damage, growth retardation, and other disorders.
Pack SizePriceUSA StockGlobal StockQuantity
5 mg$62-In Stock
10 mg$93-In Stock
25 mg$158-In Stock
50 mg$238-In Stock
100 mg$358-In Stock
500 mg$788-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.90%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Choline is the parent compound of choline compounds, with a structure in which the amino group of ethanolamine is substituted by three methyl groups. Choline acts as a neurotransmitter, nutrient, and allergen, and is an endogenous metabolite in mice, Saccharomyces cerevisiae, plants, Escherichia coli, humans, and Daphnia magna. Choline is involved in the regulation of gallbladder function, hepatic physiology, and the synthesis of the key lipid lecithin; it promotes fat and cholesterol metabolism, reduces excessive fat accumulation in the liver, and can also be used to alleviate symptoms associated with Parkinsonism and tardive dyskinesia. Choline deficiency may cause abnormal hepatic fat deposition, hypertension, gastric ulcers, liver and kidney damage, growth retardation, and other disorders.
Chemical Properties
Molecular Weight104.17
FormulaC5H14NO
Cas No.62-49-7
SmilesOCC[N+](C)(C)C
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 20 mg/mL (191.99 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM9.5997 mL47.9985 mL95.9969 mL479.9846 mL
5 mM1.9199 mL9.5997 mL19.1994 mL95.9969 mL
10 mM0.9600 mL4.7998 mL9.5997 mL47.9985 mL
20 mM0.4800 mL2.3999 mL4.7998 mL23.9992 mL
50 mM0.1920 mL0.9600 mL1.9199 mL9.5997 mL
100 mM0.0960 mL0.4800 mL0.9600 mL4.7998 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion
Related Tags: Choline chemical structure | Choline formula | Choline molecular weight