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Tetrahydrocortisone

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Catalog No. T19576Cas No. 53-05-4

Tetrahydrocortisone, the inactive metabolite of cortisone, is a product of cortisone's involvement in the stress response and its enzymatic reduction, and can be used as an indicator of cortisol metabolism.

Tetrahydrocortisone

Tetrahydrocortisone

🥰Excellent
Catalog No. T19576Cas No. 53-05-4
Tetrahydrocortisone, the inactive metabolite of cortisone, is a product of cortisone's involvement in the stress response and its enzymatic reduction, and can be used as an indicator of cortisol metabolism.
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Product Introduction

Bioactivity
Description
Tetrahydrocortisone, the inactive metabolite of cortisone, is a product of cortisone's involvement in the stress response and its enzymatic reduction, and can be used as an indicator of cortisol metabolism.
Chemical Properties
Molecular Weight364.48
FormulaC21H32O5
Cas No.53-05-4
SmilesC[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C(=O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]
Relative Density.1.0666 g/cm3 (Estimated)
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (109.75 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7436 mL13.7182 mL27.4363 mL137.1817 mL
5 mM0.5487 mL2.7436 mL5.4873 mL27.4363 mL
10 mM0.2744 mL1.3718 mL2.7436 mL13.7182 mL
20 mM0.1372 mL0.6859 mL1.3718 mL6.8591 mL
50 mM0.0549 mL0.2744 mL0.5487 mL2.7436 mL
100 mM0.0274 mL0.1372 mL0.2744 mL1.3718 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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