keep away from direct sunlight,store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 67.00 | |
5 mg | In stock | $ 107.00 | |
10 mg | In stock | $ 156.00 |
Description | MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation. |
In vitro | MAHMA NONOate (0.1 nM - 100 μM) induces concentration-dependent inhibition of collagen or ADP-induced platelet aggregation, but its potency as an aggregation inhibitor is inferior to its potency as a pulmonary vasodilator [1]. |
In vivo | MAHMA NONOate (0.3-10 nmol/kg/min; intravenous injection; once) administered to pentobarbital-anesthetized male Wistar rats resulted in dose-dependent decreases in mean systemic arterial pressure, demonstrating a more effective effect than GSNO. It also induced dose-dependent inhibition of the response to 0.3 μM/kg ADP[2]. |
Molecular Weight | 204.27 |
Formula | C8H20N4O2 |
CAS No. | 146724-86-9 |
keep away from direct sunlight,store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 40 mg/mL (195.82 mM), when pH is adjusted to 10 with NaOH. Sonication is recommended.
You can also refer to dose conversion for different animals. More
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MAHMA NONOate 146724-86-9 Immunology/Inflammation Metabolism NO Synthase Endogenous Metabolite inhibitor inhibit