cha

N3-L-Val-OH (CHA) is an azido-functionalized click chemistry reagent and a derivative of valine. Additionally, N3-L-Val-OH (CHA) serves as a synthetic intermediate for Valaciclovir (Valacyclovir).

Potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopressor activity in vivo.

d[Cha4]-AVP acetate is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopr

Phosphoenolpyruvic acid tricyclohexylammonium salt (PEP 3 CHA) is a functional carbohydrate metabolite with cytoprotective and anti-oxidative activity. Phosphoenolpyruvic acid tricyclohexylammonium salt is able to penetrate the cell membrane.

β-NETA (α-NETA) is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like receptor-1 (CMKLR1) antagonist. β-NETA has anti-cancer activity[1][2]. β-NETA weakly inhibits cholinesterase (IC50=84 µM) and acetylcholinesterase (IC50=300 µM).

N6-Cyclohexyladenosine (CHA) is a selective agonist of A1 receptor with EC50 of 8.2 Nm. N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor effects of lumbar sympathetic nerve stimulation in rats.

AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 μM). AY 77 can promote migration of human breast cancer cells in vitro.

L-Cyclohexylalanine (L-3-Cyclohexylalanine) is an amino acid analog that binds to the heavy enzyme thioester of the short peptide S synthase.L-Cyclohexylalanine can be used to synthesize anticoagulant decapeptides.

PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.

Fmoc-Cha-OH (Fmoc-L-cyclohexylalanine) is an alanine derivative containing an Fmoc protecting group, which can be used for peptide synthesis and drug design.

Fmoc-D-Cha-OH (FDCO) is an apoptotic DNase γ inhibitor that inhibits the release of HMGB1.

Ac-D-DGla-LI-Cha-C is a potent peptide inhibitor of the HCV protease, useful in research targeting various diseases, including cancer, autoimmune, fibrotic, inflammatory, neurodegenerative, infectious, lung, heart and vascular, and metabolic diseases [1].

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1) [a subtype of G-protein coupled receptors involved in mediating thrombin's cellular effects]. Exhibiting high specificity for PAR-1 over PAR-2, its selectivity was assessed via cell-based calcium signaling assays in HEK293 cells. As an agonist, it is instrumental for in vivo investigations of PAR-1 activation. PAR-1 also collaborates with PAR-4, influencing thrombin-induced hepatocellular carcinoma within [coagulation type] tumor environments where thrombin generation occurs.

N3-D-Orn(Boc)-OH (CHA) is a Boc-protected derivative of the pentanoic amino acid used in click chemistry and the synthesis of antibody-drug conjugates (ADC) [1].

Boc-L-Aza-OH CHA is a click chemistry reagent featuring an azido group.

Boc-L-Lys(N3)-OH CHA is a chemical reagent characterized by the presence of an azide group.

Boc-D-Aza-OH (CHA) serves as a click chemistry reagent, extensively utilized for linking nucleic acids, lipids, proteins, and other molecules. Click chemistry is recognized for its high yield, specificity, and simplicity, making it highly advantageous in various research fields.

N3-L-Cys(Trt)-OH (CHA) is a click chemistry reagent featuring an azide group.

Azido-PEG2-CH2COOH (CHA) is an azide-modified PEG2 acid utilized as a click chemistry reagent.

Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent that includes an azido group.

Boc-D-Lys(N3)-OH CHA is a chemical click reagent featuring an azido group. Click chemistry, known for its high yield, specificity, and simplicity, holds vast potential for applications in linking nucleic acids, lipids, proteins, and other molecules. This reagent is utilized across various research domains due to these advantageous properties.

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA is a bioactive peptide acting as a selective agonist for the protease-activated receptor 1 (PAR-1), demonstrating higher specificity for PAR-1 compared to PAR-2. PAR-1, part of the G protein-coupled receptor subfamily, is known to mediate cellular functions of thrombin. Beyond thrombin's various cellular roles, PAR-1 has been shown to interact with PAR-4, influencing thrombin-induced hepatocellular carcinoma, which forms thrombin in the tumor environment and is classified as "coagulation type."

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively.

Boc-Cha-OMe is a useful organic compound for research related to life sciences. The catalog number is T65020 and the CAS number is 98105-41-0.