cha

Potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopressor activity in vivo.

AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 μM). AY 77 can promote migration of human breast cancer cells in vitro.

L-Cyclohexylalanine (L-3-Cyclohexylalanine) is an amino acid analog that binds to the heavy enzyme thioester of the short peptide S synthase.L-Cyclohexylalanine can be used to synthesize anticoagulant decapeptides.

Fmoc-Cha-OH (Fmoc-L-cyclohexylalanine) is an alanine derivative containing an Fmoc protecting group, which can be used for peptide synthesis and drug design.

Fmoc-D-Cha-OH (FDCO) is an apoptotic DNase γ inhibitor that inhibits the release of HMGB1.

Ac-D-DGla-LI-Cha-C is a potent peptide inhibitor of the HCV protease, useful in research targeting various diseases, including cancer, autoimmune, fibrotic, inflammatory, neurodegenerative, infectious, lung, heart and vascular, and metabolic diseases [1].

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1) [a subtype of G-protein coupled receptors involved in mediating thrombin's cellular effects]. Exhibiting high specificity for PAR-1 over PAR-2, its selectivity was assessed via cell-based calcium signaling assays in HEK293 cells. As an agonist, it is instrumental for in vivo investigations of PAR-1 activation. PAR-1 also collaborates with PAR-4, influencing thrombin-induced hepatocellular carcinoma within [coagulation type] tumor environments where thrombin generation occurs.

d[Cha4]-AVP acetate is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopr

d[Cha4]-AVP TFA is a potent and selective agonist for the vasopressin (AVP) V1b receptor, with a high affinity (K i of 1.2 nM). It shows greater selectivity for the V1b receptor over the V1a receptor, V2 receptor, and oxytocin receptors, demonstrating specificity in targeting the human V1b receptor [1] [2].

Insulin β Chain Peptide (15-23), also referred to as INS, is an insulin-derived peptide specifically recognized by islet-associated T cells. The tetramer of Insulin β Chain Peptide (15-23) effectively stained the INS-reactive CTL clone G9C8; however, neither this tetramer nor the negative control tetramer (TUM) stained splenic CD8+ T cells from NOD or 8.3-TCRαβ transgenic NOD mice.

Z-Tyr(tBu)-OH.DCHA, an amino acid derivative, has a wide range of applications in life science-related research.

Z-Leu-OH.DCHA is an amino acid derivative and has a wide range of applications in life science related research.

Charybdotoxin TFA, a 37-amino acid peptide, is a K+ channel blocker [1].

Myosin H Chain Fragment, Mouse is a peptide fragment derived from the α-myosin heavy chain that serves as a critical immunogenic determinant used to induce experimental autoimmune myocarditis (EAM) in murine models. Myosin H Chain Fragment, Mouse is applied in cardiovascular immunopathology research to elucidate the mechanisms underlying autoimmune-mediated cardiac inflammation and subsequent myocardial injury.

Myosin H Chain Fragment, mouse acetate salt is a peptide segment derived from the α-myosin heavy chain and is used to induce experimental autoimmune myocarditis (EAM) in mice.

Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) acts as a substrate-specific peptide inhibitor of MLCK and inhibits hypotonicity-induced Ca2+ entry, with applications in human cervical cancer research [1] [2].

Kv3 channel protein is expressed by parvalbumin (PV)-containing pallidal neurons.Kv3, Channel Containing Protein (567-585) corresponds to amino acids 567 to 585 fragment of the Kv3.1b channel containing protein.

This peptide is a fragment of the alpha-chain of insulin amino acids 1 to 13. The insulin a-chain epitope recognized by human T cells is posttranslationally modified.

Specific inhibitor of the big conductance Ca2+-activated K+ channel.

Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a serine protease that converts soluble

Ferritin is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. Invertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21 kDA respectively. The ferritin fou

Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule

Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cell

Na+-Ca2+Exchanger inhibitory peptide (XIP) is an inhibitor of the Na+-Ca2+ exchanger with a Ki of 200 nM. It acts non-competitively to inhibit Na+-dependent Ca2+ uptake and Na+-dependent Ca2+ efflux in sarcolemmal vesicles.