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AVE-0118

Name: AVE-0118
Brand: TargetMol
SKU: T26689
Price: 67 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T26689Cas No. 498577-53-0

Alias AVE0118, AVE 0118

AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.

AVE-0118

🥰Excellent

Purity: 98.93%

Catalog No. T26689Alias AVE0118, AVE 0118Cas No. 498577-53-0

AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.

Pack Size	Price	Availability
1 mg	$67	In Stock
5 mg	$142	In Stock
10 mg	$193	In Stock
25 mg	$337	In Stock
50 mg	$498	In Stock
100 mg	$725	In Stock
500 mg	$1,520	In Stock
1 mL x 10 mM (in DMSO)	$171	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.93%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.
Synonyms	AVE0118, AVE 0118

Chemical Properties

Molecular Weight	479.57
Formula	C₃₀H₂₉N₃O₃
Cas No.	498577-53-0
Smiles	C(NCCC=1C=CC=NC1)(=O)C2=C(C=CC=C2)C3=C(CNC(CC4=CC=C(OC)C=C4)=O)C=CC=C3
Relative Density.	1.182 g/cm3 (Predicted)
Color	Orange
Appearance	Solid

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (114.69 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0852 mL	10.4260 mL	20.8520 mL	104.2601 mL
5 mM	0.4170 mL	2.0852 mL	4.1704 mL	20.8520 mL
10 mM	0.2085 mL	1.0426 mL	2.0852 mL	10.4260 mL
20 mM	0.1043 mL	0.5213 mL	1.0426 mL	5.2130 mL
50 mM	0.0417 mL	0.2085 mL	0.4170 mL	2.0852 mL
100 mM	0.0209 mL	0.1043 mL	0.2085 mL	1.0426 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc