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Nifedipine-13C8

Name: Nifedipine-13C8
Brand: TargetMol
SKU: TMID-1076
Rating: 4.5 (1 reviews)

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Catalog No. TMID-1076Cas No. 1173023-46-5

Nifedipine-13C8 is a deuterium-labeled form of Nifedipine. Nifedipine (BAY-a-1040) acts as an effective calcium channel blocker, frequently utilized in studies related to myocardial dysfunction.

Nifedipine-13C8

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Catalog No. TMID-1076Cas No. 1173023-46-5

Nifedipine-13C8 is a deuterium-labeled form of Nifedipine. Nifedipine (BAY-a-1040) acts as an effective calcium channel blocker, frequently utilized in studies related to myocardial dysfunction.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Nifedipine-13C8 is a deuterium-labeled form of Nifedipine. Nifedipine (BAY-a-1040) acts as an effective calcium channel blocker, frequently utilized in studies related to myocardial dysfunction.
In vivo	At the conclusion of the fourth week, there is a significant increase (P < 0.05) in the BL dimensions (BLi and BLk), MD dimensions (MDk), and vertical dimensions (VHi and VHk) in rats treated with Nifedipine (BAY-a-1040) (50 mg/kg) and CsA.

Chemical Properties

Molecular Weight	354.28
Formula	C₁₇H₁₈N₂O₆
Cas No.	1173023-46-5
Smiles	CO[13C]([13C]1=[13C]([13CH3])N[13C]([13CH3])=[13C]([13C](OC)=O)C1C2=C(C=CC=C2)[N+]([O-])=O)=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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You can also refer to dose conversion for different animals. More Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc