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Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody-Biotin (3O457) is a Biotin-conjugated Rabbit antibody targeting Coagulation Factor VIII/FVIII/F8 (Light Chain). Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody-Biotin (3O457) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μg | $93 | 7-10 days | 7-10 days | |
| 100 μg | $292 | 7-10 days | 7-10 days |
| Description | Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody-Biotin (3O457) is a Biotin-conjugated Rabbit antibody targeting Coagulation Factor VIII/FVIII/F8 (Light Chain). Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody-Biotin (3O457) can be used in ELISA. |
| Synonyms | THPH13, HEMA, FVIII, F8C, F8B, DXS1253E, AHF |
| Ig Type | Rabbit IgG |
| Clone | 3O457 |
| Reactivity | Human |
| Specificity | Human Factor VIII |
| Application | |
| Recommended Dose | ELISA: 0.1-1 μg/mL |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Coagulation Factor VIII / FVIII / F8 protein and then biotinylated. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Coagulation Factor VIII, also known as FVIII and F8, is a member of the multicopper oxidase family. Coagulation Factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. It contains 3 F5/8 type A domains, 2 F5/8 type C domains and 6 plastocyanin-like domains. FVIII is synthesized in the liver, and perhaps in other tissues. It is a coagulation cofactor which circulates bound to von Willebrand factor and is part of the intrinsic coagulation pathway. It is a macromolecular complex composed of two separate entities, one of which, when deficient, results in hemophilia A, and the other, when deficient, results in von Willebrand's disease. Hemophilia A is a disorder of blood coagulation characterized by a permanent tendency to hemorrhage. About 5% of patients have severe hemophilia resulting in frequent spontaneous bleeding into joints, muscles and internal organs. Less severe forms are characterized by bleeding after trauma or surgery. |
| Conjucates | Biotin |
| Others Formats | Unconjugated/HRP |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Protein: Human Coagulation Factor VIII / FVIII / F8 protein |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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