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D-myo-Inositol-2,4,5-triphosphate (Ins(2,4,5)P3) (sodium salt) is a second messenger produced by the hydrolysis of phosphatidylinositol-4,5-bisphosphate mediated by phospholipase C. Upon binding to receptors on the endoplasmic reticulum, it can open calcium channels and raise intracellular calcium ion concentrations. It also acts as a partial agonist of rat hepatic IP3 receptors. This compound is utilized in the study of calcium signaling pathways.
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | D-myo-Inositol-2,4,5-triphosphate (Ins(2,4,5)P3) (sodium salt) is a second messenger produced by the hydrolysis of phosphatidylinositol-4,5-bisphosphate mediated by phospholipase C. Upon binding to receptors on the endoplasmic reticulum, it can open calcium channels and raise intracellular calcium ion concentrations. It also acts as a partial agonist of rat hepatic IP3 receptors. This compound is utilized in the study of calcium signaling pathways. |
| Synonyms | Ins(2,4,5)P3 sodium salt, 2,4,5-IP3 sodium salt |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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